Entity Details

Primary name EF1A1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP10126
EntryNameEF1A1_MOUSE
FullNameElongation factor 1-alpha 1
TaxID10090
Evidenceevidence at protein level
Length462
SequenceStatuscomplete
DateCreated1989-07-01
DateModified2021-06-02

Ontological Relatives

GenesEef1a1

GO terms

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GOName
GO:0000049 tRNA binding
GO:0003729 mRNA binding
GO:0003746 translation elongation factor activity
GO:0003924 GTPase activity
GO:0005516 calmodulin binding
GO:0005525 GTP binding
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006412 translation
GO:0006414 translational elongation
GO:0010942 positive regulation of cell death
GO:0010976 positive regulation of neuron projection development
GO:0019900 kinase binding
GO:0019901 protein kinase binding
GO:0030864 cortical actin cytoskeleton
GO:0032587 ruffle membrane
GO:0042802 identical protein binding
GO:0043209 myelin sheath
GO:0071364 cellular response to epidermal growth factor stimulus
GO:1900022 regulation of D-erythro-sphingosine kinase activity
GO:1903427 negative regulation of reactive oxygen species biosynthetic process

Subcellular Location

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Subcellular Location
Cell membrane
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR000795 Translational (tr)-type GTP-binding domainDomainDomain
IPR004160 Translation elongation factor EFTu/EF1A, C-terminalDomainDomain
IPR004161 Translation elongation factor EFTu-like, domain 2DomainDomain
IPR004539 Translation elongation factor EF1A, eukaryotic/archaealFamilyFamily
IPR009000 Translation protein, beta-barrel domain superfamilyFamilyHomologous superfamily
IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminalFamilyHomologous superfamily
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR031157 Tr-type G domain, conserved siteSiteConserved site

Diseases

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