Entity Details

Primary name MK09_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP45984
EntryNameMK09_HUMAN
FullNameMitogen-activated protein kinase 9
TaxID9606
Evidenceevidence at protein level
Length424
SequenceStatuscomplete
DateCreated1995-11-01
DateModified2021-06-02

Ontological Relatives

GenesMAPK9

GO terms

Show/Hide Table
GOName
GO:0004674 protein serine/threonine kinase activity
GO:0004705 JUN kinase activity
GO:0004707 MAP kinase activity
GO:0004712 protein serine/threonine/tyrosine kinase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005829 cytosol
GO:0006468 protein phosphorylation
GO:0007254 JNK cascade
GO:0008134 transcription factor binding
GO:0010628 positive regulation of gene expression
GO:0010744 positive regulation of macrophage derived foam cell differentiation
GO:0018105 peptidyl-serine phosphorylation
GO:0031398 positive regulation of protein ubiquitination
GO:0034614 cellular response to reactive oxygen species
GO:0035556 intracellular signal transduction
GO:0038095 Fc-epsilon receptor signaling pathway
GO:0042752 regulation of circadian rhythm
GO:0048511 rhythmic process
GO:0051090 regulation of DNA-binding transcription factor activity
GO:0061833 protein localization to tricellular tight junction
GO:0071276 cellular response to cadmium ion
GO:0071803 positive regulation of podosome assembly
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:1901485 positive regulation of transcription factor catabolic process
GO:2001235 positive regulation of apoptotic signaling pathway

Subcellular Location

Show/Hide Table
Subcellular Location
Cytoplasm
Nucleus

Domains

Show/Hide Table
DomainNameCategoryType
IPR000719 Protein kinase domainDomainDomain
IPR003527 Mitogen-activated protein (MAP) kinase, conserved siteSiteConserved site
IPR008271 Serine/threonine-protein kinase, active siteSiteActive site
IPR008351 Mitogen-activated protein (MAP) kinase, JNKFamilyFamily
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily

Diseases

Show/Hide Table

Drugs

Show/Hide Table
DrugNameSourceType
DB01017 MinocyclineDrugbanksmall molecule
DB07020 N-{3-[5-(1H-1,2,4-triazol-3-yl)-1H-indazol-3-yl]phenyl}furan-2-carboxamideDrugbanksmall molecule
DB12010 FostamatinibDrugbanksmall molecule
DB15624 HalicinDrugbanksmall molecule