Entity Details

Primary name YAP1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP46937
EntryNameYAP1_HUMAN
FullNameTranscriptional coactivator YAP1
TaxID9606
Evidenceevidence at protein level
Length504
SequenceStatuscomplete
DateCreated1995-11-01
DateModified2021-06-02

Ontological Relatives

GenesYAP1

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000902 cell morphogenesis
GO:0000976 transcription cis-regulatory region binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0001570 vasculogenesis
GO:0001674 female germ cell nucleus
GO:0001829 trophectodermal cell differentiation
GO:0001894 tissue homeostasis
GO:0003015 heart process
GO:0003143 embryonic heart tube morphogenesis
GO:0003682 chromatin binding
GO:0003713 transcription coactivator activity
GO:0003714 transcription corepressor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006367 transcription initiation from RNA polymerase II promoter
GO:0006974 cellular response to DNA damage stimulus
GO:0007399 nervous system development
GO:0008022 protein C-terminus binding
GO:0008283 cell population proliferation
GO:0010628 positive regulation of gene expression
GO:0010629 negative regulation of gene expression
GO:0010837 regulation of keratinocyte proliferation
GO:0016020 membrane
GO:0030216 keratinocyte differentiation
GO:0030857 negative regulation of epithelial cell differentiation
GO:0030903 notochord development
GO:0032570 response to progesterone
GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway
GO:0035019 somatic stem cell population maintenance
GO:0035329 hippo signaling
GO:0042060 wound healing
GO:0045599 negative regulation of fat cell differentiation
GO:0045669 positive regulation of osteoblast differentiation
GO:0045747 positive regulation of Notch signaling pathway
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048339 paraxial mesoderm development
GO:0048368 lateral mesoderm development
GO:0050679 positive regulation of epithelial cell proliferation
GO:0050767 regulation of neurogenesis
GO:0050847 progesterone receptor signaling pathway
GO:0060045 positive regulation of cardiac muscle cell proliferation
GO:0060242 contact inhibition
GO:0060449 bud elongation involved in lung branching
GO:0060487 lung epithelial cell differentiation
GO:0060576 intestinal epithelial cell development
GO:0061026 cardiac muscle tissue regeneration
GO:0065003 protein-containing complex assembly
GO:0070064 proline-rich region binding
GO:0070102 interleukin-6-mediated signaling pathway
GO:0071300 cellular response to retinoic acid
GO:0071480 cellular response to gamma radiation
GO:0072091 regulation of stem cell proliferation
GO:0072307 regulation of metanephric nephron tubule epithelial cell differentiation
GO:0090263 positive regulation of canonical Wnt signaling pathway
GO:0140297 DNA-binding transcription factor binding
GO:0140552 TEAD-YAP complex
GO:1900182 positive regulation of protein localization to nucleus
GO:1902018 negative regulation of cilium assembly
GO:1902036 regulation of hematopoietic stem cell differentiation
GO:1902459 positive regulation of stem cell population maintenance
GO:1904036 negative regulation of epithelial cell apoptotic process
GO:2000737 negative regulation of stem cell differentiation
GO:2001237 negative regulation of extrinsic apoptotic signaling pathway

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR001202 WW domainDomainDomain
IPR036020 WW domain superfamilyFamilyHomologous superfamily

Diseases

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