Entity Details

Primary name TITIN_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionA2ASS6
EntryNameTITIN_MOUSE
FullNameTitin
TaxID10090
Evidenceevidence at protein level
Length35213
SequenceStatuscomplete
DateCreated2007-11-13
DateModified2021-06-02

Ontological Relatives

GO terms

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GOName
GO:0000794 condensed nuclear chromosome
GO:0001701 in utero embryonic development
GO:0001756 somitogenesis
GO:0002020 protease binding
GO:0003007 heart morphogenesis
GO:0003300 cardiac muscle hypertrophy
GO:0004674 protein serine/threonine kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0005200 structural constituent of cytoskeleton
GO:0005509 calcium ion binding
GO:0005516 calmodulin binding
GO:0005524 ATP binding
GO:0005859 muscle myosin complex
GO:0005865 striated muscle thin filament
GO:0006936 muscle contraction
GO:0007507 heart development
GO:0007512 adult heart development
GO:0008307 structural constituent of muscle
GO:0010628 positive regulation of gene expression
GO:0010737 protein kinase A signaling
GO:0019899 enzyme binding
GO:0019901 protein kinase binding
GO:0021591 ventricular system development
GO:0030016 myofibril
GO:0030017 sarcomere
GO:0030018 Z disc
GO:0030240 skeletal muscle thin filament assembly
GO:0030241 skeletal muscle myosin thick filament assembly
GO:0030506 ankyrin binding
GO:0031430 M band
GO:0031433 telethonin binding
GO:0031672 A band
GO:0031674 I band
GO:0035995 detection of muscle stretch
GO:0042802 identical protein binding
GO:0042805 actinin binding
GO:0043056 forward locomotion
GO:0043621 protein self-association
GO:0045214 sarcomere organization
GO:0045859 regulation of protein kinase activity
GO:0048769 sarcomerogenesis
GO:0050714 positive regulation of protein secretion
GO:0050790 regulation of catalytic activity
GO:0051015 actin filament binding
GO:0051371 muscle alpha-actinin binding
GO:0051592 response to calcium ion
GO:0055002 striated muscle cell development
GO:0055003 cardiac myofibril assembly
GO:0055008 cardiac muscle tissue morphogenesis
GO:0060048 cardiac muscle contraction
GO:0060419 heart growth
GO:0097493 structural molecule activity conferring elasticity
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:1901897 regulation of relaxation of cardiac muscle

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR000719 Protein kinase domainDomainDomain
IPR003598 Immunoglobulin subtype 2DomainDomain
IPR003599 Immunoglobulin subtypeDomainDomain
IPR003961 Fibronectin type IIIDomainDomain
IPR004168 PPAK motifRepeatRepeat
IPR007110 Immunoglobulin-like domainDomainDomain
IPR008266 Tyrosine-protein kinase, active siteSiteActive site
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily
IPR013098 Immunoglobulin I-setDomainDomain
IPR013106 Immunoglobulin V-set domainDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR015129 Titin, Z repeatRepeatRepeat
IPR036116 Fibronectin type III superfamilyFamilyHomologous superfamily
IPR036179 Immunoglobulin-like domain superfamilyFamilyHomologous superfamily
IPR040849 MyBP-C, tri-helix bundle domainDomainDomain

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
TITIN_MOUSEANKR1_MOUSEMINT24515436 details
TITIN_MOUSESYNEM_MOUSEMINT25447537 details