Entity Details

Primary name TAU_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP10637
EntryNameTAU_MOUSE
FullNameMicrotubule-associated protein tau
TaxID10090
Evidenceevidence at protein level
Length733
SequenceStatuscomplete
DateCreated1989-07-01
DateModified2021-06-02

Ontological Relatives

GenesMapt

GO terms

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GOName
GO:0000226 microtubule cytoskeleton organization
GO:0001764 neuron migration
GO:0003677 DNA binding
GO:0005576 extracellular region
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005874 microtubule
GO:0005886 plasma membrane
GO:0005930 axoneme
GO:0006915 apoptotic process
GO:0007409 axonogenesis
GO:0007416 synapse assembly
GO:0007584 response to nutrient
GO:0007611 learning or memory
GO:0007613 memory
GO:0007628 adult walking behavior
GO:0008017 microtubule binding
GO:0008088 axo-dendritic transport
GO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress
GO:0009898 cytoplasmic side of plasma membrane
GO:0010033 response to organic substance
GO:0010288 response to lead ion
GO:0010506 regulation of autophagy
GO:0010629 negative regulation of gene expression
GO:0010917 negative regulation of mitochondrial membrane potential
GO:0010976 positive regulation of neuron projection development
GO:0014069 postsynaptic density
GO:0015630 microtubule cytoskeleton
GO:0016607 nuclear speck
GO:0017124 SH3 domain binding
GO:0019899 enzyme binding
GO:0019901 protein kinase binding
GO:0030424 axon
GO:0030425 dendrite
GO:0030426 growth cone
GO:0030673 axolemma
GO:0031072 heat shock protein binding
GO:0031110 regulation of microtubule polymerization or depolymerization
GO:0031116 positive regulation of microtubule polymerization
GO:0031175 neuron projection development
GO:0032387 negative regulation of intracellular transport
GO:0032930 positive regulation of superoxide anion generation
GO:0033673 negative regulation of kinase activity
GO:0034185 apolipoprotein binding
GO:0034399 nuclear periphery
GO:0036464 cytoplasmic ribonucleoprotein granule
GO:0036477 somatodendritic compartment
GO:0042802 identical protein binding
GO:0043005 neuron projection
GO:0043025 neuronal cell body
GO:0044295 axonal growth cone
GO:0044297 cell body
GO:0044304 main axon
GO:0044877 protein-containing complex binding
GO:0045121 membrane raft
GO:0045298 tubulin complex
GO:0045773 positive regulation of axon extension
GO:0046785 microtubule polymerization
GO:0047497 mitochondrion transport along microtubule
GO:0048312 intracellular distribution of mitochondria
GO:0048675 axon extension
GO:0050808 synapse organization
GO:0050848 regulation of calcium-mediated signaling
GO:0051028 mRNA transport
GO:0051087 chaperone binding
GO:0051258 protein polymerization
GO:0051260 protein homooligomerization
GO:0051721 protein phosphatase 2A binding
GO:0051879 Hsp90 protein binding
GO:0060632 regulation of microtubule-based movement
GO:0070507 regulation of microtubule cytoskeleton organization
GO:0071813 lipoprotein particle binding
GO:0090258 negative regulation of mitochondrial fission
GO:0097386 glial cell projection
GO:0097418 neurofibrillary tangle
GO:0097435 supramolecular fiber organization
GO:0099609 microtubule lateral binding
GO:1900034 regulation of cellular response to heat
GO:1900454 positive regulation of long-term synaptic depression
GO:1901216 positive regulation of neuron death
GO:1902474 positive regulation of protein localization to synapse
GO:1903748 negative regulation of establishment of protein localization to mitochondrion
GO:1903829 positive regulation of cellular protein localization
GO:1904428 negative regulation of tubulin deacetylation
GO:1990000 amyloid fibril formation
GO:2001020 regulation of response to DNA damage stimulus

Subcellular Location

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Subcellular Location
Cell membrane
Cell projection
Cytoplasm
Secreted

Domains

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DomainNameCategoryType
IPR001084 Microtubule associated protein, tubulin-binding repeatRepeatRepeat
IPR002955 Microtubule-associated protein TauFamilyFamily

Diseases

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