Entity Details

Primary name CDK8_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP49336
EntryNameCDK8_HUMAN
FullNameCyclin-dependent kinase 8
TaxID9606
Evidenceevidence at protein level
Length464
SequenceStatuscomplete
DateCreated1996-02-01
DateModified2021-06-02

Ontological Relatives

GenesCDK8

GO terms

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GOName
GO:0004672 protein kinase activity
GO:0004693 cyclin-dependent protein serine/threonine kinase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0006468 protein phosphorylation
GO:0008353 RNA polymerase II CTD heptapeptide repeat kinase activity
GO:0016592 mediator complex
GO:0032991 protein-containing complex
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0060260 regulation of transcription initiation from RNA polymerase II promoter
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR000719 Protein kinase domainDomainDomain
IPR008271 Serine/threonine-protein kinase, active siteSiteActive site
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily
IPR017441 Protein kinase, ATP binding siteSiteBinding site

Diseases

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Drugs

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DrugNameSourceType
DB03496 AlvocidibDrugbanksmall molecule

Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink