Entity Details

Primary name TCPG_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP49368
EntryNameTCPG_HUMAN
FullNameT-complex protein 1 subunit gamma
TaxID9606
Evidenceevidence at protein level
Length545
SequenceStatuscomplete
DateCreated1996-02-01
DateModified2021-06-02

Ontological Relatives

GenesCCT3

GO terms

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GOName
GO:0002199 zona pellucida receptor complex
GO:0003723 RNA binding
GO:0005524 ATP binding
GO:0005829 cytosol
GO:0005832 chaperonin-containing T-complex
GO:0005856 cytoskeleton
GO:0005874 microtubule
GO:0006457 protein folding
GO:0007339 binding of sperm to zona pellucida
GO:0016887 ATP hydrolysis activity
GO:0032212 positive regulation of telomere maintenance via telomerase
GO:0044183 protein folding chaperone
GO:0044297 cell body
GO:0046931 pore complex assembly
GO:0050821 protein stabilization
GO:0051082 unfolded protein binding
GO:0070062 extracellular exosome
GO:1901998 toxin transport
GO:1904851 positive regulation of establishment of protein localization to telomere
GO:1904871 positive regulation of protein localization to Cajal body
GO:1904874 positive regulation of telomerase RNA localization to Cajal body

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR002194 Chaperonin TCP-1, conserved siteSiteConserved site
IPR002423 Chaperonin Cpn60/TCP-1 familyFamilyFamily
IPR012719 T-complex protein 1, gamma subunitFamilyFamily
IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1)FamilyFamily
IPR027409 GroEL-like apical domain superfamilyFamilyHomologous superfamily
IPR027410 TCP-1-like chaperonin intermediate domain superfamilyFamilyHomologous superfamily
IPR027413 GroEL-like equatorial domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB04395 Phosphoaminophosphonic Acid-Adenylate EsterDrugbanksmall molecule
DB11638 ArtenimolDrugbanksmall molecule

Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
TCPG_HUMANMK13_MOUSEBioGRID19135240 details
TCPG_HUMANOSTM1_MOUSEBioGRID26598607 details