Entity Details

Primary name EFTU_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP49411
EntryNameEFTU_HUMAN
FullNameElongation factor Tu, mitochondrial
TaxID9606
Evidenceevidence at protein level
Length452
SequenceStatuscomplete
DateCreated1996-02-01
DateModified2021-06-02

Ontological Relatives

GenesTUFM

GO terms

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GOName
GO:0003723 RNA binding
GO:0003746 translation elongation factor activity
GO:0003924 GTPase activity
GO:0005525 GTP binding
GO:0005739 mitochondrion
GO:0006414 translational elongation
GO:0016020 membrane
GO:0016032 viral process
GO:0042645 mitochondrial nucleoid
GO:0045202 synapse
GO:0045471 response to ethanol
GO:0070062 extracellular exosome
GO:0070125 mitochondrial translational elongation

Subcellular Location

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Subcellular Location
Mitochondrion

Domains

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DomainNameCategoryType
IPR000795 Translational (tr)-type GTP-binding domainDomainDomain
IPR004160 Translation elongation factor EFTu/EF1A, C-terminalDomainDomain
IPR004161 Translation elongation factor EFTu-like, domain 2DomainDomain
IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelleFamilyFamily
IPR009000 Translation protein, beta-barrel domain superfamilyFamilyHomologous superfamily
IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminalFamilyHomologous superfamily
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR031157 Tr-type G domain, conserved siteSiteConserved site
IPR033720 Elongation factor Tu, domain 2DomainDomain
IPR041709 Elongation factor Tu (EF-Tu), GTP-binding domainDomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB01593 ZincDrugbanksmall molecule
DB04315 Guanosine-5'-DiphosphateDrugbanksmall molecule
DB14487 Zinc acetateDrugbanksmall molecule
DB14533 Zinc chlorideDrugbanksmall molecule
DB14548 Zinc sulfate, unspecified formDrugbanksmall molecule

Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink