Entity Details

Primary name AL7A1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP49419
EntryNameAL7A1_HUMAN
FullNameAlpha-aminoadipic semialdehyde dehydrogenase
TaxID9606
Evidenceevidence at protein level
Length539
SequenceStatuscomplete
DateCreated1996-02-01
DateModified2021-06-02

Ontological Relatives

GenesALDH7A1

GO terms

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GOName
GO:0004029 aldehyde dehydrogenase (NAD+) activity
GO:0004043 L-aminoadipate-semialdehyde dehydrogenase activity
GO:0005634 nucleus
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0005829 cytosol
GO:0006081 cellular aldehyde metabolic process
GO:0006554 lysine catabolic process
GO:0007605 sensory perception of sound
GO:0008802 betaine-aldehyde dehydrogenase activity
GO:0019285 glycine betaine biosynthetic process from choline
GO:0042426 choline catabolic process
GO:0042802 identical protein binding
GO:0043878 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity
GO:0070062 extracellular exosome

Subcellular Location

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Subcellular Location
Cytoplasm
Mitochondrion
Nucleus

Domains

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DomainNameCategoryType
IPR015590 Aldehyde dehydrogenase domainDomainDomain
IPR016161 Aldehyde/histidinol dehydrogenaseFamilyHomologous superfamily
IPR016162 Aldehyde dehydrogenase, N-terminalFamilyHomologous superfamily
IPR016163 Aldehyde dehydrogenase, C-terminalFamilyHomologous superfamily
IPR029510 Aldehyde dehydrogenase, glutamic acid active siteSiteConserved site
IPR044638 Aldehyde dehydrogenase family 7 member A1-likeFamilyFamily

Diseases

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Drugs

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DrugNameSourceType
DB00157 NADHDrugbanksmall molecule
DB11638 ArtenimolDrugbanksmall molecule

Interactions

0 interactions

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