Entity Details

Primary name CENPF_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP49454
EntryNameCENPF_HUMAN
FullNameCentromere protein F
TaxID9606
Evidenceevidence at protein level
Length3114
SequenceStatuscomplete
DateCreated1996-02-01
DateModified2021-06-02

Ontological Relatives

GenesCENPF

GO terms

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GOName
GO:0000278 mitotic cell cycle
GO:0000775 chromosome, centromeric region
GO:0000776 kinetochore
GO:0000922 spindle pole
GO:0000940 outer kinetochore
GO:0001822 kidney development
GO:0003682 chromatin binding
GO:0005634 nucleus
GO:0005635 nuclear envelope
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0005819 spindle
GO:0005829 cytosol
GO:0005930 axoneme
GO:0007052 mitotic spindle organization
GO:0007059 chromosome segregation
GO:0007094 mitotic spindle assembly checkpoint signaling
GO:0007517 muscle organ development
GO:0008017 microtubule binding
GO:0008022 protein C-terminus binding
GO:0008134 transcription factor binding
GO:0010389 regulation of G2/M transition of mitotic cell cycle
GO:0015031 protein transport
GO:0016202 regulation of striated muscle tissue development
GO:0016363 nuclear matrix
GO:0021591 ventricular system development
GO:0030154 cell differentiation
GO:0030496 midbody
GO:0036064 ciliary basal body
GO:0042493 response to drug
GO:0042803 protein homodimerization activity
GO:0045120 pronucleus
GO:0045892 negative regulation of transcription, DNA-templated
GO:0048471 perinuclear region of cytoplasm
GO:0051301 cell division
GO:0051310 metaphase plate congression
GO:0051382 kinetochore assembly
GO:0051726 regulation of cell cycle
GO:0070840 dynein complex binding
GO:0071897 DNA biosynthetic process
GO:0097539 ciliary transition fiber

Subcellular Location

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Subcellular Location
Chromosome
Cytoplasm
Nucleus matrix

Domains

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DomainNameCategoryType
IPR018302 Kinetochore protein Cenp-F/LEK1, Rb protein-binding domainDomainDomain
IPR018463 Centromere protein Cenp-F, N-terminalDomainDomain
IPR019513 Centromere protein Cenp-F, leucine-rich repeat-containing domainDomainDomain
IPR043513 Centromere protein Cenp-FFamilyFamily

Diseases

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Interactions

0 interactions

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