Entity Details

Primary name CEBPA_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP49715
EntryNameCEBPA_HUMAN
FullNameCCAAT/enhancer-binding protein alpha
TaxID9606
Evidenceevidence at protein level
Length358
SequenceStatuscomplete
DateCreated1996-10-01
DateModified2021-06-02

Ontological Relatives

GenesCEBPA

GO terms

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GOName
GO:0000050 urea cycle
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000976 transcription cis-regulatory region binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001163 RNA polymerase I transcription regulatory region sequence-specific DNA binding
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001889 liver development
GO:0001892 embryonic placenta development
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005667 transcription regulator complex
GO:0005730 nucleolus
GO:0006091 generation of precursor metabolites and energy
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006360 transcription by RNA polymerase I
GO:0007005 mitochondrion organization
GO:0007219 Notch signaling pathway
GO:0008134 transcription factor binding
GO:0008203 cholesterol metabolic process
GO:0008285 negative regulation of cell population proliferation
GO:0010628 positive regulation of gene expression
GO:0016032 viral process
GO:0019221 cytokine-mediated signaling pathway
GO:0019900 kinase binding
GO:0030099 myeloid cell differentiation
GO:0030225 macrophage differentiation
GO:0030324 lung development
GO:0030851 granulocyte differentiation
GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0042593 glucose homeostasis
GO:0042803 protein homodimerization activity
GO:0043032 positive regulation of macrophage activation
GO:0043231 intracellular membrane-bounded organelle
GO:0045444 fat cell differentiation
GO:0045600 positive regulation of fat cell differentiation
GO:0045669 positive regulation of osteoblast differentiation
GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0045945 positive regulation of transcription by RNA polymerase III
GO:0048469 cell maturation
GO:0048839 inner ear development
GO:0050729 positive regulation of inflammatory response
GO:0050872 white fat cell differentiation
GO:0050873 brown fat cell differentiation
GO:0055088 lipid homeostasis
GO:0070102 interleukin-6-mediated signaling pathway
GO:0071285 cellular response to lithium ion
GO:0071356 cellular response to tumor necrosis factor
GO:0071407 cellular response to organic cyclic compound
GO:0090575 RNA polymerase II transcription regulator complex
GO:2000144 positive regulation of DNA-templated transcription, initiation

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR004827 Basic-leucine zipper domainDomainDomain
IPR016468 CCAAT/enhancer-binding protein, chordatesFamilyFamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
CEBPA_HUMANFBXW7_MOUSEBioGRID20534483 details