Entity Details

Primary name GNAQ_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP50148
EntryNameGNAQ_HUMAN
FullNameGuanine nucleotide-binding protein G(q) subunit alpha
TaxID9606
Evidenceevidence at protein level
Length359
SequenceStatuscomplete
DateCreated1996-10-01
DateModified2021-06-02

Ontological Relatives

GenesGNAQ

GO terms

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GOName
GO:0001508 action potential
GO:0001664 G protein-coupled receptor binding
GO:0001750 photoreceptor outer segment
GO:0003924 GTPase activity
GO:0005096 GTPase activator activity
GO:0005525 GTP binding
GO:0005737 cytoplasm
GO:0005765 lysosomal membrane
GO:0005794 Golgi apparatus
GO:0005834 heterotrimeric G-protein complex
GO:0005886 plasma membrane
GO:0006469 negative regulation of protein kinase activity
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway
GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway
GO:0007202 activation of phospholipase C activity
GO:0007213 G protein-coupled acetylcholine receptor signaling pathway
GO:0007215 glutamate receptor signaling pathway
GO:0007596 blood coagulation
GO:0007603 phototransduction, visible light
GO:0009649 entrainment of circadian clock
GO:0030168 platelet activation
GO:0031683 G-protein beta/gamma-subunit complex binding
GO:0031826 type 2A serotonin receptor binding
GO:0031965 nuclear membrane
GO:0045202 synapse
GO:0046872 metal ion binding
GO:0050821 protein stabilization
GO:0060828 regulation of canonical Wnt signaling pathway
GO:0070062 extracellular exosome

Subcellular Location

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Subcellular Location
Cell membrane
Golgi apparatus
Nucleus
Nucleus membrane

Domains

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DomainNameCategoryType
IPR000654 G-protein alpha subunit, group QFamilyFamily
IPR001019 Guanine nucleotide binding protein (G-protein), alpha subunitFamilyFamily
IPR011025 G protein alpha subunit, helical insertionFamilyHomologous superfamily
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
GNAQ_HUMANRIC8B_MOUSEBioGRID20133939 details