Entity Details

Primary name TNF10_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP50591
EntryNameTNF10_HUMAN
FullNameTumor necrosis factor ligand superfamily member 10
TaxID9606
Evidenceevidence at protein level
Length281
SequenceStatuscomplete
DateCreated1996-10-01
DateModified2021-06-02

Ontological Relatives

GenesTNFSF10

GO terms

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GOName
GO:0005102 signaling receptor binding
GO:0005125 cytokine activity
GO:0005164 tumor necrosis factor receptor binding
GO:0005576 extracellular region
GO:0005887 integral component of plasma membrane
GO:0006915 apoptotic process
GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0006955 immune response
GO:0007165 signal transduction
GO:0007166 cell surface receptor signaling pathway
GO:0007267 cell-cell signaling
GO:0008270 zinc ion binding
GO:0008584 male gonad development
GO:0032868 response to insulin
GO:0042802 identical protein binding
GO:0043065 positive regulation of apoptotic process
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0045569 TRAIL binding
GO:0070062 extracellular exosome
GO:0090200 positive regulation of release of cytochrome c from mitochondria
GO:1902041 regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:2001238 positive regulation of extrinsic apoptotic signaling pathway

Subcellular Location

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Subcellular Location
Cell membrane
Secreted

Domains

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DomainNameCategoryType
IPR006052 Tumour necrosis factor domainDomainDomain
IPR008983 Tumour necrosis factor-like domain superfamilyFamilyHomologous superfamily
IPR017355 Tumour necrosis factor ligand 10/11FamilyFamily
IPR021184 Tumour necrosis factor, conserved siteSiteConserved site

Diseases

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Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink