Entity Details

Primary name FXR1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP51114
EntryNameFXR1_HUMAN
FullNameFragile X mental retardation syndrome-related protein 1
TaxID9606
Evidenceevidence at protein level
Length621
SequenceStatuscomplete
DateCreated1996-10-01
DateModified2021-06-02

Ontological Relatives

GenesFXR1

GO terms

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GOName
GO:0000381 regulation of alternative mRNA splicing, via spliceosome
GO:0001934 positive regulation of protein phosphorylation
GO:0003723 RNA binding
GO:0003730 mRNA 3'-UTR binding
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005844 polysome
GO:0006915 apoptotic process
GO:0007517 muscle organ development
GO:0014069 postsynaptic density
GO:0016020 membrane
GO:0017148 negative regulation of translation
GO:0030154 cell differentiation
GO:0030424 axon
GO:0030426 growth cone
GO:0033592 RNA strand annealing activity
GO:0036464 cytoplasmic ribonucleoprotein granule
GO:0042803 protein homodimerization activity
GO:0043025 neuronal cell body
GO:0043034 costamere
GO:0043197 dendritic spine
GO:0043488 regulation of mRNA stability
GO:0044326 dendritic spine neck
GO:0045182 translation regulator activity
GO:0045727 positive regulation of translation
GO:0046982 protein heterodimerization activity
GO:0048471 perinuclear region of cytoplasm
GO:0051489 regulation of filopodium assembly
GO:0060538 skeletal muscle organ development
GO:0098793 presynapse
GO:0098978 glutamatergic synapse
GO:1902737 dendritic filopodium
GO:2000637 positive regulation of gene silencing by miRNA
GO:2001022 positive regulation of response to DNA damage stimulus

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR004087 K Homology domainDomainDomain
IPR004088 K Homology domain, type 1DomainDomain
IPR008395 Agenet-like domainDomainDomain
IPR022034 Fragile X-related 1 protein, C-terminal coreDomainDomain
IPR032172 Fragile X-related 1 protein, C-terminal region 1DomainDomain
IPR032177 Fragile X-related 1 protein, C-terminal region 3DomainDomain
IPR036612 K Homology domain, type 1 superfamilyFamilyHomologous superfamily
IPR040148 Fragile X mental retardation syndrome-related proteinFamilyFamily
IPR040472 Synaptic functional regulator FMRP, KH0 domainDomainDomain
IPR041560 Fxr1, tudor domainDomainDomain

Diseases

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Interactions

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