Entity Details

Primary name CCR4_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP51679
EntryNameCCR4_HUMAN
FullNameC-C chemokine receptor type 4
TaxID9606
Evidenceevidence at protein level
Length360
SequenceStatuscomplete
DateCreated1996-10-01
DateModified2021-06-02

Ontological Relatives

GenesCCR4

GO terms

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GOName
GO:0001764 neuron migration
GO:0002507 tolerance induction
GO:0004950 chemokine receptor activity
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006935 chemotaxis
GO:0006954 inflammatory response
GO:0006955 immune response
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0009314 response to radiation
GO:0009617 response to bacterium
GO:0009897 external side of plasma membrane
GO:0016493 C-C chemokine receptor activity
GO:0019722 calcium-mediated signaling
GO:0019957 C-C chemokine binding
GO:0043025 neuronal cell body
GO:0046677 response to antibiotic
GO:0048872 homeostasis of number of cells
GO:0050927 positive regulation of positive chemotaxis
GO:0060326 cell chemotaxis

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR000276 G protein-coupled receptor, rhodopsin-likeFamilyFamily
IPR000355 Chemokine receptor familyFamilyFamily
IPR002239 CC chemokine receptor 4FamilyFamily
IPR017452 GPCR, rhodopsin-like, 7TMDomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB12498 MogamulizumabDrugbankbiotech
DB15570 FLX475Drugbanksmall molecule

Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
CCR4_HUMANCNOT7_MOUSEMINT18337750 details