Entity Details

Primary name CLCN2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP51788
EntryNameCLCN2_HUMAN
FullNameChloride channel protein 2
TaxID9606
Evidenceevidence at protein level
Length898
SequenceStatuscomplete
DateCreated1996-10-01
DateModified2021-06-02

Ontological Relatives

GenesCLCN2

GO terms

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GOName
GO:0005247 voltage-gated chloride channel activity
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006821 chloride transport
GO:0032347 regulation of aldosterone biosynthetic process
GO:0034220 ion transmembrane transport
GO:0034707 chloride channel complex
GO:0034765 regulation of ion transmembrane transport
GO:0060041 retina development in camera-type eye
GO:0060689 cell differentiation involved in salivary gland development

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR000644 CBS domainDomainDomain
IPR001807 Chloride channel, voltage gatedFamilyFamily
IPR002244 Chloride channel ClC-2FamilyFamily
IPR014743 Chloride channel, coreFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB01046 LubiprostoneDrugbanksmall molecule
DB05514 CobiprostoneDrugbanksmall molecule

Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
CLCN2_HUMANHACD3_MOUSEIntAct25036637 details
CLCN2_HUMANUBP19_MOUSEIntAct25036637 details