Entity Details

Primary name IMA1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP52292
EntryNameIMA1_HUMAN
FullNameImportin subunit alpha-1
TaxID9606
Evidenceevidence at protein level
Length529
SequenceStatuscomplete
DateCreated1996-10-01
DateModified2021-06-02

Ontological Relatives

GenesKPNA2

GO terms

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GOName
GO:0000018 regulation of DNA recombination
GO:0000139 Golgi membrane
GO:0003723 RNA binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005789 endoplasmic reticulum membrane
GO:0005829 cytosol
GO:0006259 DNA metabolic process
GO:0006302 double-strand break repair
GO:0006607 NLS-bearing protein import into nucleus
GO:0008139 nuclear localization sequence binding
GO:0016020 membrane
GO:0019054 modulation by virus of host cellular process
GO:0042826 histone deacetylase binding
GO:0043657 host cell
GO:0061608 nuclear import signal receptor activity
GO:0075506 entry of viral genome into host nucleus through nuclear pore complex via importin
GO:0098892 extrinsic component of postsynaptic specialization membrane
GO:0098978 glutamatergic synapse
GO:0099527 postsynapse to nucleus signaling pathway
GO:1903902 positive regulation of viral life cycle

Subcellular Location

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Subcellular Location
Cytoplasm
Endoplasmic reticulum membrane
Golgi apparatus membrane
Nucleus

Domains

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DomainNameCategoryType
IPR000225 ArmadilloRepeatRepeat
IPR002652 Importin-alpha, importin-beta-binding domainDomainDomain
IPR011989 Armadillo-like helicalFamilyHomologous superfamily
IPR016024 Armadillo-type foldFamilyHomologous superfamily
IPR024931 Importin subunit alphaFamilyFamily
IPR032413 Atypical Arm repeatRepeatRepeat
IPR036975 Importin-alpha, importin-beta-binding domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

4 interactions