Entity Details

Primary name GDIR1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP52565
EntryNameGDIR1_HUMAN
FullNameRho GDP-dissociation inhibitor 1
TaxID9606
Evidenceevidence at protein level
Length204
SequenceStatuscomplete
DateCreated1996-10-01
DateModified2021-06-02

Ontological Relatives

GenesARHGDIA

GO terms

Show/Hide Table
GOName
GO:0005094 Rho GDP-dissociation inhibitor activity
GO:0005096 GTPase activator activity
GO:0005829 cytosol
GO:0005856 cytoskeleton
GO:0007162 negative regulation of cell adhesion
GO:0007266 Rho protein signal transduction
GO:0016020 membrane
GO:0035023 regulation of Rho protein signal transduction
GO:0043066 negative regulation of apoptotic process
GO:0043547 positive regulation of GTPase activity
GO:0050771 negative regulation of axonogenesis
GO:0050772 positive regulation of axonogenesis
GO:0051056 regulation of small GTPase mediated signal transduction
GO:0070062 extracellular exosome
GO:0071526 semaphorin-plexin signaling pathway
GO:2000249 regulation of actin cytoskeleton reorganization

Subcellular Location

Show/Hide Table
Subcellular Location
Cytoplasm

Domains

Show/Hide Table
DomainNameCategoryType
IPR000406 Rho protein GDP-dissociation inhibitorFamilyFamily
IPR014756 Immunoglobulin E-setFamilyHomologous superfamily
IPR024792 Rho GDP-dissociation inhibitor domain superfamilyFamilyHomologous superfamily

Diseases

Show/Hide Table

Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
GDIR1_HUMANRAC1_MOUSEMINT22157745 details