Entity Details

Primary name GPX1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP11352
EntryNameGPX1_MOUSE
FullNameGlutathione peroxidase 1
TaxID10090
Evidenceevidence at protein level
Length201
SequenceStatuscomplete
DateCreated1989-07-01
DateModified2021-06-02

Ontological Relatives

GenesGpx1

GO terms

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GOName
GO:0000302 response to reactive oxygen species
GO:0001659 temperature homeostasis
GO:0001885 endothelial cell development
GO:0002862 negative regulation of inflammatory response to antigenic stimulus
GO:0004601 peroxidase activity
GO:0004602 glutathione peroxidase activity
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005829 cytosol
GO:0006629 lipid metabolic process
GO:0006641 triglyceride metabolic process
GO:0006749 glutathione metabolic process
GO:0006979 response to oxidative stress
GO:0007605 sensory perception of sound
GO:0008283 cell population proliferation
GO:0009410 response to xenobiotic stimulus
GO:0009609 response to symbiotic bacterium
GO:0009611 response to wounding
GO:0009636 response to toxic substance
GO:0009650 UV protection
GO:0010269 response to selenium ion
GO:0010332 response to gamma radiation
GO:0014902 myotube differentiation
GO:0017124 SH3 domain binding
GO:0018158 protein oxidation
GO:0019369 arachidonic acid metabolic process
GO:0019372 lipoxygenase pathway
GO:0033194 response to hydroperoxide
GO:0033599 regulation of mammary gland epithelial cell proliferation
GO:0040029 regulation of gene expression, epigenetic
GO:0042311 vasodilation
GO:0042542 response to hydrogen peroxide
GO:0042744 hydrogen peroxide catabolic process
GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043403 skeletal muscle tissue regeneration
GO:0043534 blood vessel endothelial cell migration
GO:0045444 fat cell differentiation
GO:0045454 cell redox homeostasis
GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity
GO:0048741 skeletal muscle fiber development
GO:0051450 myoblast proliferation
GO:0051702 biological process involved in interaction with symbiont
GO:0051897 positive regulation of protein kinase B signaling
GO:0060047 heart contraction
GO:0060055 angiogenesis involved in wound healing
GO:0061136 regulation of proteasomal protein catabolic process
GO:0071333 cellular response to glucose stimulus
GO:0090201 negative regulation of release of cytochrome c from mitochondria
GO:0097413 Lewy body
GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:1902176 negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR000889 Glutathione peroxidaseFamilyFamily
IPR029759 Glutathione peroxidase active siteSiteActive site
IPR029760 Glutathione peroxidase conserved siteSiteConserved site
IPR036249 Thioredoxin-like superfamilyFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
GPX1_MOUSEHCD2_HUMANBioGRID22496890 details