Entity Details

Primary name HAP1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP54257
EntryNameHAP1_HUMAN
FullNameHuntingtin-associated protein 1
TaxID9606
Evidenceevidence at protein level
Length671
SequenceStatuscomplete
DateCreated1996-10-01
DateModified2021-06-02

Ontological Relatives

GenesHAP1

GO terms

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GOName
GO:0005102 signaling receptor binding
GO:0005730 nucleolus
GO:0005739 mitochondrion
GO:0005764 lysosome
GO:0005769 early endosome
GO:0005776 autophagosome
GO:0005783 endoplasmic reticulum
GO:0005813 centrosome
GO:0005814 centriole
GO:0005829 cytosol
GO:0005856 cytoskeleton
GO:0006605 protein targeting
GO:0006887 exocytosis
GO:0006914 autophagy
GO:0007268 chemical synaptic transmission
GO:0007420 brain development
GO:0008021 synaptic vesicle
GO:0008089 anterograde axonal transport
GO:0008090 retrograde axonal transport
GO:0008104 protein localization
GO:0015629 actin cytoskeleton
GO:0016234 inclusion body
GO:0017022 myosin binding
GO:0017157 regulation of exocytosis
GO:0021549 cerebellum development
GO:0021979 hypothalamus cell differentiation
GO:0022008 neurogenesis
GO:0030030 cell projection organization
GO:0030425 dendrite
GO:0030426 growth cone
GO:0031410 cytoplasmic vesicle
GO:0031587 positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
GO:0032230 positive regulation of synaptic transmission, GABAergic
GO:0032901 positive regulation of neurotrophin production
GO:0043197 dendritic spine
GO:0044325 transmembrane transporter binding
GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway
GO:0047496 vesicle transport along microtubule
GO:0048011 neurotrophin TRK receptor signaling pathway
GO:0048311 mitochondrion distribution
GO:0048403 brain-derived neurotrophic factor binding
GO:0050769 positive regulation of neurogenesis
GO:0098957 anterograde axonal transport of mitochondrion
GO:1902430 negative regulation of amyloid-beta formation
GO:1902513 regulation of organelle transport along microtubule
GO:1902857 positive regulation of non-motile cilium assembly
GO:1904115 axon cytoplasm

Subcellular Location

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Subcellular Location
Cell junction
Cell projection
Cytoplasm
Cytoplasmic vesicle
Early endosome
Endoplasmic reticulum
Lysosome
Mitochondrion
Nucleus

Domains

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DomainNameCategoryType
IPR006933 HAP1, N-terminalDomainDomain

Diseases

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Interactions

1 interaction

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HAP1_HUMANKALRN_MOUSEUniProt18192679 details