Entity Details

Primary name KAD2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP54819
EntryNameKAD2_HUMAN
FullNameAdenylate kinase 2, mitochondrial
TaxID9606
Evidenceevidence at protein level
Length239
SequenceStatuscomplete
DateCreated1996-10-01
DateModified2021-06-02

Ontological Relatives

GenesAK2

GO terms

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GOName
GO:0004017 adenylate kinase activity
GO:0005524 ATP binding
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005758 mitochondrial intermembrane space
GO:0006172 ADP biosynthetic process
GO:0015949 nucleobase-containing small molecule interconversion
GO:0046033 AMP metabolic process
GO:0046034 ATP metabolic process
GO:0070062 extracellular exosome
GO:0097226 sperm mitochondrial sheath

Subcellular Location

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Subcellular Location
Mitochondrion intermembrane space

Domains

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DomainNameCategoryType
IPR000850 Adenylate kinase/UMP-CMP kinaseFamilyFamily
IPR006259 Adenylate kinase subfamilyFamilyFamily
IPR007862 Adenylate kinase, active site lid domainDomainDomain
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR028587 Adenylate kinase 2FamilyFamily
IPR033690 Adenylate kinase, conserved siteSiteConserved site

Diseases

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Drugs

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DrugNameSourceType
DB00300 Tenofovir disoproxilDrugbanksmall molecule
DB00718 Adefovir dipivoxilDrugbanksmall molecule
DB01717 Bis(Adenosine)-5'-PentaphosphateDrugbanksmall molecule
DB03366 ImidazoleDrugbanksmall molecule
DB09299 Tenofovir alafenamideDrugbanksmall molecule
DB14126 TenofovirDrugbanksmall molecule

Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink