Entity Details

Primary name CDK1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP11440
EntryNameCDK1_MOUSE
FullNameCyclin-dependent kinase 1
TaxID10090
Evidenceevidence at protein level
Length297
SequenceStatuscomplete
DateCreated1989-10-01
DateModified2021-06-02

Ontological Relatives

GenesCdk1

GO terms

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GOName
GO:0000086 G2/M transition of mitotic cell cycle
GO:0000307 cyclin-dependent protein kinase holoenzyme complex
GO:0003682 chromatin binding
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004693 cyclin-dependent protein serine/threonine kinase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005813 centrosome
GO:0005829 cytosol
GO:0005876 spindle microtubule
GO:0006468 protein phosphorylation
GO:0006915 apoptotic process
GO:0007095 mitotic G2 DNA damage checkpoint signaling
GO:0007569 cell aging
GO:0008283 cell population proliferation
GO:0008353 RNA polymerase II CTD heptapeptide repeat kinase activity
GO:0009636 response to toxic substance
GO:0010243 response to organonitrogen compound
GO:0010628 positive regulation of gene expression
GO:0010629 negative regulation of gene expression
GO:0010971 positive regulation of G2/M transition of mitotic cell cycle
GO:0014070 response to organic cyclic compound
GO:0014075 response to amine
GO:0014823 response to activity
GO:0016301 kinase activity
GO:0018105 peptidyl-serine phosphorylation
GO:0018107 peptidyl-threonine phosphorylation
GO:0030261 chromosome condensation
GO:0030332 cyclin binding
GO:0030496 midbody
GO:0030544 Hsp70 protein binding
GO:0031100 animal organ regeneration
GO:0034501 protein localization to kinetochore
GO:0035173 histone kinase activity
GO:0042307 positive regulation of protein import into nucleus
GO:0042493 response to drug
GO:0042752 regulation of circadian rhythm
GO:0043066 negative regulation of apoptotic process
GO:0044772 mitotic cell cycle phase transition
GO:0045471 response to ethanol
GO:0045740 positive regulation of DNA replication
GO:0045931 positive regulation of mitotic cell cycle
GO:0046686 response to cadmium ion
GO:0046688 response to copper ion
GO:0048511 rhythmic process
GO:0048678 response to axon injury
GO:0051301 cell division
GO:0055015 ventricular cardiac muscle cell development
GO:0060045 positive regulation of cardiac muscle cell proliferation
GO:0065003 protein-containing complex assembly
GO:0070301 cellular response to hydrogen peroxide
GO:0072686 mitotic spindle
GO:0090166 Golgi disassembly
GO:0097125 cyclin B1-CDK1 complex
GO:0097472 cyclin-dependent protein kinase activity
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:1900182 positive regulation of protein localization to nucleus
GO:1905448 positive regulation of mitochondrial ATP synthesis coupled electron transport

Subcellular Location

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Subcellular Location
Cytoplasm
Mitochondrion
Nucleus

Domains

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DomainNameCategoryType
IPR000719 Protein kinase domainDomainDomain
IPR008271 Serine/threonine-protein kinase, active siteSiteActive site
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily
IPR017441 Protein kinase, ATP binding siteSiteBinding site

Diseases

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