Entity Details

Primary name TERA_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP55072
EntryNameTERA_HUMAN
FullNameTransitional endoplasmic reticulum ATPase
TaxID9606
Evidenceevidence at protein level
Length806
SequenceStatuscomplete
DateCreated1996-10-01
DateModified2021-06-02

Ontological Relatives

GenesVCP

GO terms

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GOName
GO:0000502 proteasome complex
GO:0003723 RNA binding
GO:0005524 ATP binding
GO:0005576 extracellular region
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005811 lipid droplet
GO:0005829 cytosol
GO:0006281 DNA repair
GO:0006302 double-strand break repair
GO:0006457 protein folding
GO:0006734 NADH metabolic process
GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport
GO:0006914 autophagy
GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0006974 cellular response to DNA damage stimulus
GO:0008289 lipid binding
GO:0010494 cytoplasmic stress granule
GO:0010498 proteasomal protein catabolic process
GO:0010918 positive regulation of mitochondrial membrane potential
GO:0016236 macroautophagy
GO:0016567 protein ubiquitination
GO:0016579 protein deubiquitination
GO:0016887 ATP hydrolysis activity
GO:0019079 viral genome replication
GO:0019903 protein phosphatase binding
GO:0019904 protein domain specific binding
GO:0019985 translesion synthesis
GO:0030433 ubiquitin-dependent ERAD pathway
GO:0030968 endoplasmic reticulum unfolded protein response
GO:0030970 retrograde protein transport, ER to cytosol
GO:0031334 positive regulation of protein-containing complex assembly
GO:0031593 polyubiquitin modification-dependent protein binding
GO:0031625 ubiquitin protein ligase binding
GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway
GO:0032991 protein-containing complex
GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex
GO:0034605 cellular response to heat
GO:0034774 secretory granule lumen
GO:0035578 azurophil granule lumen
GO:0035617 stress granule disassembly
GO:0035800 deubiquitinase activator activity
GO:0035861 site of double-strand break
GO:0036297 interstrand cross-link repair
GO:0036435 K48-linked polyubiquitin modification-dependent protein binding
GO:0036503 ERAD pathway
GO:0036513 Derlin-1 retrotranslocation complex
GO:0042288 MHC class I protein binding
GO:0042802 identical protein binding
GO:0042981 regulation of apoptotic process
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0043231 intracellular membrane-bounded organelle
GO:0043312 neutrophil degranulation
GO:0043531 ADP binding
GO:0044389 ubiquitin-like protein ligase binding
GO:0045184 establishment of protein localization
GO:0045732 positive regulation of protein catabolic process
GO:0045879 negative regulation of smoothened signaling pathway
GO:0046034 ATP metabolic process
GO:0048471 perinuclear region of cytoplasm
GO:0050807 regulation of synapse organization
GO:0051228 mitotic spindle disassembly
GO:0055085 transmembrane transport
GO:0061857 endoplasmic reticulum stress-induced pre-emptive quality control
GO:0070062 extracellular exosome
GO:0070842 aggresome assembly
GO:0070987 error-free translesion synthesis
GO:0071712 ER-associated misfolded protein catabolic process
GO:0072389 flavin adenine dinucleotide catabolic process
GO:0090263 positive regulation of canonical Wnt signaling pathway
GO:0097352 autophagosome maturation
GO:0098978 glutamatergic synapse
GO:0106300 protein-DNA covalent cross-linking repair
GO:1903006 positive regulation of protein K63-linked deubiquitination
GO:1903007 positive regulation of Lys63-specific deubiquitinase activity
GO:1903715 regulation of aerobic respiration
GO:1903843 cellular response to arsenite ion
GO:1903862 positive regulation of oxidative phosphorylation
GO:1904288 BAT3 complex binding
GO:1904813 ficolin-1-rich granule lumen
GO:1904949 ATPase complex
GO:1905634 regulation of protein localization to chromatin
GO:1990381 ubiquitin-specific protease binding
GO:1990730 VCP-NSFL1C complex
GO:2001171 positive regulation of ATP biosynthetic process

Subcellular Location

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Subcellular Location
Cytoplasm
Endoplasmic reticulum
Nucleus

Domains

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DomainNameCategoryType
IPR003338 CDC48, N-terminal subdomainDomainDomain
IPR003593 AAA+ ATPase domainDomainDomain
IPR003959 ATPase, AAA-type, coreDomainDomain
IPR003960 ATPase, AAA-type, conserved siteSiteConserved site
IPR004201 CDC48, domain 2DomainDomain
IPR005938 AAA ATPase, CDC48 familyFamilyFamily
IPR009010 Aspartate decarboxylase-like domain superfamilyFamilyHomologous superfamily
IPR015415 Vps4 oligomerisation, C-terminalDomainDomain
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR029067 CDC48 domain 2-like superfamilyFamilyHomologous superfamily
IPR041569 AAA ATPase, AAA+ lid domainDomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB04395 Phosphoaminophosphonic Acid-Adenylate EsterDrugbanksmall molecule
DB12695 Phenethyl IsothiocyanateDrugbanksmall molecule