Entity Details

Primary name CASP7_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP55210
EntryNameCASP7_HUMAN
FullNameCaspase-7
TaxID9606
Evidenceevidence at protein level
Length303
SequenceStatuscomplete
DateCreated1996-10-01
DateModified2021-06-02

Ontological Relatives

GenesCASP7

GO terms

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GOName
GO:0004197 cysteine-type endopeptidase activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006508 proteolysis
GO:0006915 apoptotic process
GO:0008233 peptidase activity
GO:0008234 cysteine-type peptidase activity
GO:0072734 cellular response to staurosporine
GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process
GO:0097194 execution phase of apoptosis
GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR001309 Peptidase C14, p20 domainDomainDomain
IPR002138 Peptidase C14, caspase non-catalytic subunit p10DomainDomain
IPR002398 Peptidase C14 familyFamilyFamily
IPR015471 Caspase-3/7FamilyFamily
IPR015917 Peptidase C14A, caspase catalytic domainDomainDomain
IPR016129 Peptidase family C14A, His active siteSiteActive site
IPR029030 Caspase-like domain superfamilyFamilyHomologous superfamily
IPR033139 Peptidase family C14A, cysteine active siteSiteActive site

Diseases

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Drugs

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DrugNameSourceType
DB03384 FicaDrugbanksmall molecule
DB05408 EmricasanDrugbanksmall molecule
DB06255 Incadronic acidDrugbanksmall molecule

Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
CASP7_HUMANGRAB_MOUSEBioGRID17283187 details