Entity Details

Primary name CASP9_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP55211
EntryNameCASP9_HUMAN
FullNameCaspase-9
TaxID9606
Evidenceevidence at protein level
Length416
SequenceStatuscomplete
DateCreated1996-10-01
DateModified2021-06-02

Ontological Relatives

GenesCASP9

GO terms

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GOName
GO:0004197 cysteine-type endopeptidase activity
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006915 apoptotic process
GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0006974 cellular response to DNA damage stimulus
GO:0008047 enzyme activator activity
GO:0008233 peptidase activity
GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage
GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c
GO:0017124 SH3 domain binding
GO:0019901 protein kinase binding
GO:0030220 platelet formation
GO:0032991 protein-containing complex
GO:0034644 cellular response to UV
GO:0042770 signal transduction in response to DNA damage
GO:0042802 identical protein binding
GO:0043065 positive regulation of apoptotic process
GO:0043293 apoptosome
GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process
GO:0097192 extrinsic apoptotic signaling pathway in absence of ligand
GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway
GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis
GO:2001020 regulation of response to DNA damage stimulus

Subcellular Location

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Domains

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DomainNameCategoryType
IPR001309 Peptidase C14, p20 domainDomainDomain
IPR001315 CARD domainDomainDomain
IPR002138 Peptidase C14, caspase non-catalytic subunit p10DomainDomain
IPR002398 Peptidase C14 familyFamilyFamily
IPR011029 Death-like domain superfamilyFamilyHomologous superfamily
IPR015917 Peptidase C14A, caspase catalytic domainDomainDomain
IPR016129 Peptidase family C14A, His active siteSiteActive site
IPR029030 Caspase-like domain superfamilyFamilyHomologous superfamily
IPR033139 Peptidase family C14A, cysteine active siteSiteActive site
IPR033171 Caspase-9FamilyFamily
IPR042147 CASP9, CARD domainDomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB00282 Pamidronic acidDrugbanksmall molecule

Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
CASP9_HUMANCDON_MOUSEDIP23940460 details