Entity Details

Primary name BID_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP55957
EntryNameBID_HUMAN
FullNameBH3-interacting domain death agonist
TaxID9606
Evidenceevidence at protein level
Length195
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesBID

GO terms

Show/Hide Table
GOName
GO:0001836 release of cytochrome c from mitochondria
GO:0005123 death receptor binding
GO:0005739 mitochondrion
GO:0005741 mitochondrial outer membrane
GO:0005829 cytosol
GO:0006626 protein targeting to mitochondrion
GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors
GO:0008637 apoptotic mitochondrial changes
GO:0010918 positive regulation of mitochondrial membrane potential
GO:0016020 membrane
GO:0031334 positive regulation of protein-containing complex assembly
GO:0031625 ubiquitin protein ligase binding
GO:0032592 integral component of mitochondrial membrane
GO:0042127 regulation of cell population proliferation
GO:0042770 signal transduction in response to DNA damage
GO:0042775 mitochondrial ATP synthesis coupled electron transport
GO:0042981 regulation of apoptotic process
GO:0043065 positive regulation of apoptotic process
GO:0043066 negative regulation of apoptotic process
GO:0051402 neuron apoptotic process
GO:0065003 protein-containing complex assembly
GO:0090150 establishment of protein localization to membrane
GO:0090200 positive regulation of release of cytochrome c from mitochondria
GO:0097284 hepatocyte apoptotic process
GO:0097345 mitochondrial outer membrane permeabilization
GO:1900740 positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
GO:1901030 positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
GO:2000045 regulation of G1/S transition of mitotic cell cycle
GO:2000271 positive regulation of fibroblast apoptotic process
GO:2001238 positive regulation of extrinsic apoptotic signaling pathway
GO:2001244 positive regulation of intrinsic apoptotic signaling pathway

Subcellular Location

Show/Hide Table
Subcellular Location
Cytoplasm
Mitochondrion membrane
Mitochondrion outer membrane

Domains

Show/Hide Table
DomainNameCategoryType
IPR010479 BH3-interacting domain death agonistFamilyFamily
IPR020728 Apoptosis regulator, Bcl-2, BH3 motif, conserved siteSiteConserved site
IPR036834 Bcl-2-like superfamilyFamilyHomologous superfamily

Diseases

Show/Hide Table

Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
BID_HUMANB2LA1_MOUSEIntAct15694340 17289999 details