Entity Details

Primary name L1CAM_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP11627
EntryNameL1CAM_MOUSE
FullNameNeural cell adhesion molecule L1
TaxID10090
Evidenceevidence at protein level
Length1260
SequenceStatuscomplete
DateCreated1989-10-01
DateModified2021-06-02

Ontological Relatives

GO terms

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GOName
GO:0005178 integrin binding
GO:0005768 endosome
GO:0005886 plasma membrane
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
GO:0007159 leukocyte cell-cell adhesion
GO:0007160 cell-matrix adhesion
GO:0007166 cell surface receptor signaling pathway
GO:0007411 axon guidance
GO:0007413 axonal fasciculation
GO:0008046 axon guidance receptor activity
GO:0009897 external side of plasma membrane
GO:0009986 cell surface
GO:0010811 positive regulation of cell-substrate adhesion
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0016477 cell migration
GO:0019904 protein domain specific binding
GO:0022409 positive regulation of cell-cell adhesion
GO:0030165 PDZ domain binding
GO:0030424 axon
GO:0030425 dendrite
GO:0031175 neuron projection development
GO:0033631 cell-cell adhesion mediated by integrin
GO:0033691 sialic acid binding
GO:0034109 homotypic cell-cell adhesion
GO:0042734 presynaptic membrane
GO:0042802 identical protein binding
GO:0043025 neuronal cell body
GO:0043195 terminal bouton
GO:0043621 protein self-association
GO:0044294 dendritic growth cone
GO:0044295 axonal growth cone
GO:0045121 membrane raft
GO:0045773 positive regulation of axon extension
GO:0050804 modulation of chemical synaptic transmission
GO:0050808 synapse organization
GO:0050850 positive regulation of calcium-mediated signaling
GO:0061564 axon development
GO:0070372 regulation of ERK1 and ERK2 cascade
GO:0098685 Schaffer collateral - CA1 synapse

Subcellular Location

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Subcellular Location
Cell membrane
Cell projection

Domains

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DomainNameCategoryType
IPR003598 Immunoglobulin subtype 2DomainDomain
IPR003599 Immunoglobulin subtypeDomainDomain
IPR003961 Fibronectin type IIIDomainDomain
IPR007110 Immunoglobulin-like domainDomainDomain
IPR013098 Immunoglobulin I-setDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR026966 Neurofascin/L1/NrCAM, C-terminal domainDomainDomain
IPR036116 Fibronectin type III superfamilyFamilyHomologous superfamily
IPR036179 Immunoglobulin-like domain superfamilyFamilyHomologous superfamily

Diseases

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