Entity Details

Primary name OAS1A_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP11928
EntryNameOAS1A_MOUSE
FullName2'-5'-oligoadenylate synthase 1A
TaxID10090
Evidenceevidence at protein level
Length367
SequenceStatuscomplete
DateCreated1989-10-01
DateModified2021-06-02

Ontological Relatives

GenesOas1a

GO terms

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GOName
GO:0001730 2'-5'-oligoadenylate synthetase activity
GO:0003725 double-stranded RNA binding
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005783 endoplasmic reticulum
GO:0005829 cytosol
GO:0006164 purine nucleotide biosynthetic process
GO:0009615 response to virus
GO:0016020 membrane
GO:0045071 negative regulation of viral genome replication
GO:0045087 innate immune response
GO:0046872 metal ion binding
GO:0048525 negative regulation of viral process
GO:0051607 defense response to virus
GO:0060700 regulation of ribonuclease activity

Subcellular Location

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Subcellular Location
Cytoplasm
Endoplasmic reticulum
Microsome
Mitochondrion
Nucleus

Domains

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DomainNameCategoryType
IPR002934 Polymerase, nucleotidyl transferase domainDomainDomain
IPR006116 2-5OAS/ClassI-CCAase, nucleotidyltransferase domainDomainDomain
IPR006117 2-5-oligoadenylate synthetase, C-terminal conserved siteSiteConserved site
IPR018952 2'-5'-oligoadenylate synthetase 1, domain 2/C-terminalDomainDomain
IPR026774 2'-5'-oligoadenylate synthaseFamilyFamily
IPR043518 2-5-oligoadenylate synthetase, N-terminal conserved siteSiteConserved site
IPR043519 Nucleotidyltransferase superfamilyFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
OAS1A_MOUSEOAS1D_MOUSEBioGRID15899864 details