Entity Details

Primary name UBE2N_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP61088
EntryNameUBE2N_HUMAN
FullNameUbiquitin-conjugating enzyme E2 N
TaxID9606
Evidenceevidence at protein level
Length152
SequenceStatuscomplete
DateCreated2004-04-26
DateModified2021-06-02

Ontological Relatives

GenesUBE2N

GO terms

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GOName
GO:0000151 ubiquitin ligase complex
GO:0000187 obsolete activation of MAPK activity
GO:0000209 protein polyubiquitination
GO:0000724 double-strand break repair via homologous recombination
GO:0000729 DNA double-strand break processing
GO:0001650 fibrillar center
GO:0003723 RNA binding
GO:0004842 ubiquitin-protein transferase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006282 regulation of DNA repair
GO:0006301 postreplication repair
GO:0006302 double-strand break repair
GO:0006303 double-strand break repair via nonhomologous end joining
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0007254 JNK cascade
GO:0016567 protein ubiquitination
GO:0016574 histone ubiquitination
GO:0031058 positive regulation of histone modification
GO:0031372 UBC13-MMS2 complex
GO:0031625 ubiquitin protein ligase binding
GO:0032991 protein-containing complex
GO:0033182 regulation of histone ubiquitination
GO:0035370 UBC13-UEV1A complex
GO:0035973 aggrephagy
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043130 ubiquitin binding
GO:0045739 positive regulation of DNA repair
GO:0050852 T cell receptor signaling pathway
GO:0051092 positive regulation of NF-kappaB transcription factor activity
GO:0051443 positive regulation of ubiquitin-protein transferase activity
GO:0061631 ubiquitin conjugating enzyme activity
GO:0070062 extracellular exosome
GO:0070423 nucleotide-binding oligomerization domain containing signaling pathway
GO:0070498 interleukin-1-mediated signaling pathway
GO:0070534 protein K63-linked ubiquitination

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR000608 Ubiquitin-conjugating enzyme E2DomainDomain
IPR016135 Ubiquitin-conjugating enzyme/RWD-likeFamilyHomologous superfamily
IPR023313 Ubiquitin-conjugating enzyme, active siteSiteActive site

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
UBE2N_HUMANCHIP_MOUSEBioGRID, UniProt16307917 details
UBE2N_HUMANTRAF6_MOUSEBioGRID15147900 17709375 28993672 details