Entity Details

Primary name ARP3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP61158
EntryNameARP3_HUMAN
FullNameActin-related protein 3
TaxID9606
Evidenceevidence at protein level
Length418
SequenceStatuscomplete
DateCreated2004-05-10
DateModified2021-06-02

Ontological Relatives

GenesACTR3

GO terms

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GOName
GO:0003779 actin binding
GO:0005200 structural constituent of cytoskeleton
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005885 Arp2/3 protein complex
GO:0005903 brush border
GO:0005911 cell-cell junction
GO:0005925 focal adhesion
GO:0007163 establishment or maintenance of cell polarity
GO:0008356 asymmetric cell division
GO:0010592 positive regulation of lamellipodium assembly
GO:0015629 actin cytoskeleton
GO:0016020 membrane
GO:0016344 meiotic chromosome movement towards spindle pole
GO:0030027 lamellipodium
GO:0033206 meiotic cytokinesis
GO:0034314 Arp2/3 complex-mediated actin nucleation
GO:0035861 site of double-strand break
GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048013 ephrin receptor signaling pathway
GO:0051653 spindle localization
GO:0060271 cilium assembly
GO:0061024 membrane organization
GO:0070062 extracellular exosome
GO:0070358 actin polymerization-dependent cell motility
GO:0071346 cellular response to interferon-gamma

Subcellular Location

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Subcellular Location
Cell projection
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR004000 Actin familyFamilyFamily
IPR015623 Actin-related protein 3FamilyFamily
IPR020902 Actin/actin-like conserved siteSiteConserved site
IPR043129 ATPase, nucleotide binding domainFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB08235 N-[2-(2-methyl-1H-indol-3-yl)ethyl]thiophene-2-carboxamideDrugbanksmall molecule
DB08236 (2S)-2-(3-bromophenyl)-3-(5-chloro-2-hydroxyphenyl)-1,3-thiazolidin-4-oneDrugbanksmall molecule

Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
ARP3_HUMANSRC8_MOUSEmbinfo11231575 details
ARP3_HUMANDNM1L_MOUSEMINT31063459 details