Entity Details

Primary name PFKAL_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP12382
EntryNamePFKAL_MOUSE
FullNameATP-dependent 6-phosphofructokinase, liver type
TaxID10090
Evidenceevidence at protein level
Length780
SequenceStatuscomplete
DateCreated1989-10-01
DateModified2021-06-02

Ontological Relatives

GenesPfkl

GO terms

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GOName
GO:0003872 6-phosphofructokinase activity
GO:0005524 ATP binding
GO:0005829 cytosol
GO:0005945 6-phosphofructokinase complex
GO:0005975 carbohydrate metabolic process
GO:0006002 fructose 6-phosphate metabolic process
GO:0006096 glycolytic process
GO:0009749 response to glucose
GO:0016020 membrane
GO:0016208 AMP binding
GO:0019900 kinase binding
GO:0030388 fructose 1,6-bisphosphate metabolic process
GO:0042802 identical protein binding
GO:0046676 negative regulation of insulin secretion
GO:0046872 metal ion binding
GO:0048029 monosaccharide binding
GO:0061615 glycolytic process through fructose-6-phosphate
GO:0061621 canonical glycolysis
GO:0070061 fructose binding
GO:0070095 fructose-6-phosphate binding

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR000023 Phosphofructokinase domainDomainDomain
IPR009161 ATP-dependent 6-phosphofructokinase, eukaryotic-typeFamilyFamily
IPR015912 Phosphofructokinase, conserved siteSiteConserved site
IPR022953 ATP-dependent 6-phosphofructokinaseFamilyFamily
IPR035966 Phosphofructokinase superfamilyFamilyHomologous superfamily
IPR041914 ATP-dependent 6-phosphofructokinase, vertebrate-typeFamilyFamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
PFKAL_MOUSEITA2B_MOUSEBioGRID30333137 details
PFKAL_MOUSENMDZ1_MOUSEBioGRID, IntAct10862698 16635246 details