Entity Details

Primary name WDR5_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP61964
EntryNameWDR5_HUMAN
FullNameWD repeat-containing protein 5
TaxID9606
Evidenceevidence at protein level
Length334
SequenceStatuscomplete
DateCreated2004-06-07
DateModified2021-06-02

Ontological Relatives

GenesWDR5

GO terms

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GOName
GO:0000123 histone acetyltransferase complex
GO:0001501 skeletal system development
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex
GO:0031175 neuron projection development
GO:0035064 methylated histone binding
GO:0035097 histone methyltransferase complex
GO:0042393 histone binding
GO:0043687 post-translational protein modification
GO:0043966 histone H3 acetylation
GO:0043981 histone H4-K5 acetylation
GO:0043982 histone H4-K8 acetylation
GO:0043984 histone H4-K16 acetylation
GO:0044666 MLL3/4 complex
GO:0045652 regulation of megakaryocyte differentiation
GO:0045722 positive regulation of gluconeogenesis
GO:0048188 Set1C/COMPASS complex
GO:0051568 histone H3-K4 methylation
GO:0051571 positive regulation of histone H3-K4 methylation
GO:0051572 negative regulation of histone H3-K4 methylation
GO:0071339 MLL1 complex

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR001680 WD40 repeatRepeatRepeat
IPR015943 WD40/YVTN repeat-like-containing domain superfamilyFamilyHomologous superfamily
IPR019775 WD40 repeat, conserved siteSiteConserved site
IPR020472 G-protein beta WD-40 repeatRepeatRepeat
IPR036322 WD40-repeat-containing domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
WDR5_HUMANBMAL1_MOUSEIntAct23555304 details
WDR5_HUMANBHE41_MOUSEIntAct23555304 details