Entity Details

Primary name HNRPK_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP61978
EntryNameHNRPK_HUMAN
FullNameHeterogeneous nuclear ribonucleoprotein K
TaxID9606
Evidenceevidence at protein level
Length463
SequenceStatuscomplete
DateCreated2004-06-07
DateModified2021-06-02

Ontological Relatives

GenesHNRNPK

GO terms

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GOName
GO:0000398 mRNA splicing, via spliceosome
GO:0000785 chromatin
GO:0002102 podosome
GO:0003677 DNA binding
GO:0003723 RNA binding
GO:0003729 mRNA binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005925 focal adhesion
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006396 RNA processing
GO:0007165 signal transduction
GO:0010468 regulation of gene expression
GO:0010494 cytoplasmic stress granule
GO:0010988 regulation of low-density lipoprotein particle clearance
GO:0016020 membrane
GO:0016070 RNA metabolic process
GO:0019058 viral life cycle
GO:0019904 protein domain specific binding
GO:0042802 identical protein binding
GO:0042995 cell projection
GO:0043066 negative regulation of apoptotic process
GO:0045296 cadherin binding
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048024 regulation of mRNA splicing, via spliceosome
GO:0048025 negative regulation of mRNA splicing, via spliceosome
GO:0048260 positive regulation of receptor-mediated endocytosis
GO:0070062 extracellular exosome
GO:0071013 catalytic step 2 spliceosome
GO:1902165 regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:1905599 positive regulation of low-density lipoprotein receptor activity

Subcellular Location

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Subcellular Location
Cell projection
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR004087 K Homology domainDomainDomain
IPR004088 K Homology domain, type 1DomainDomain
IPR012987 ROK, N-terminalDomainDomain
IPR033090 Heterogeneous nuclear ribonucleoprotein KFamilyFamily
IPR036612 K Homology domain, type 1 superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB11638 ArtenimolDrugbanksmall molecule
DB12695 Phenethyl IsothiocyanateDrugbanksmall molecule

Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
HNRPK_HUMANHMGB1_MOUSEMINT11748221 details
HNRPK_HUMANMK13_MOUSEBioGRID19135240 details