Entity Details

Primary name 1433E_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP62258
EntryName1433E_HUMAN
FullName14-3-3 protein epsilon
TaxID9606
Evidenceevidence at protein level
Length255
SequenceStatuscomplete
DateCreated2004-07-05
DateModified2021-06-02

Ontological Relatives

GenesYWHAE

GO terms

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GOName
GO:0000086 G2/M transition of mitotic cell cycle
GO:0000165 MAPK cascade
GO:0003064 regulation of heart rate by hormone
GO:0003723 RNA binding
GO:0005246 calcium channel regulator activity
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005829 cytosol
GO:0005871 kinesin complex
GO:0005925 focal adhesion
GO:0010389 regulation of G2/M transition of mitotic cell cycle
GO:0015459 potassium channel regulator activity
GO:0016020 membrane
GO:0016032 viral process
GO:0019899 enzyme binding
GO:0021762 substantia nigra development
GO:0023026 MHC class II protein complex binding
GO:0031625 ubiquitin protein ligase binding
GO:0034504 protein localization to nucleus
GO:0034605 cellular response to heat
GO:0035329 hippo signaling
GO:0035556 intracellular signal transduction
GO:0042470 melanosome
GO:0042802 identical protein binding
GO:0042826 histone deacetylase binding
GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0044325 transmembrane transporter binding
GO:0045296 cadherin binding
GO:0046827 positive regulation of protein export from nucleus
GO:0046982 protein heterodimerization activity
GO:0050815 phosphoserine residue binding
GO:0051219 phosphoprotein binding
GO:0051480 regulation of cytosolic calcium ion concentration
GO:0060306 regulation of membrane repolarization
GO:0070062 extracellular exosome
GO:0086013 membrane repolarization during cardiac muscle cell action potential
GO:0086091 regulation of heart rate by cardiac conduction
GO:0090724 central region of growth cone
GO:0097110 scaffold protein binding
GO:0097711 ciliary basal body-plasma membrane docking
GO:0098978 glutamatergic synapse
GO:0099072 regulation of postsynaptic membrane neurotransmitter receptor levels
GO:1900034 regulation of cellular response to heat
GO:1900740 positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
GO:1901016 regulation of potassium ion transmembrane transporter activity
GO:1901020 negative regulation of calcium ion transmembrane transporter activity
GO:1902309 negative regulation of peptidyl-serine dephosphorylation
GO:1905913 negative regulation of calcium ion export across plasma membrane

Subcellular Location

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Subcellular Location
Cytoplasm
Melanosome
Nucleus

Domains

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DomainNameCategoryType
IPR000308 14-3-3 proteinFamilyFamily
IPR023409 14-3-3 protein, conserved siteSiteConserved site
IPR023410 14-3-3 domainDomainDomain
IPR036815 14-3-3 domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB01780 FusicoccinDrugbanksmall molecule
DB12695 Phenethyl IsothiocyanateDrugbanksmall molecule