Entity Details

Primary name RPB7_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP62487
EntryNameRPB7_HUMAN
FullNameDNA-directed RNA polymerase II subunit RPB7
TaxID9606
Evidenceevidence at protein level
Length172
SequenceStatuscomplete
DateCreated2004-07-19
DateModified2021-06-02

Ontological Relatives

GenesPOLR2G

GO terms

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GOName
GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic
GO:0000398 mRNA splicing, via spliceosome
GO:0000932 P-body
GO:0003697 single-stranded DNA binding
GO:0003727 single-stranded RNA binding
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005665 RNA polymerase II, core complex
GO:0006283 transcription-coupled nucleotide-excision repair
GO:0006351 transcription, DNA-templated
GO:0006366 transcription by RNA polymerase II
GO:0006367 transcription initiation from RNA polymerase II promoter
GO:0006368 transcription elongation from RNA polymerase II promoter
GO:0006370 7-methylguanosine mRNA capping
GO:0006915 apoptotic process
GO:0008543 fibroblast growth factor receptor signaling pathway
GO:0016070 RNA metabolic process
GO:0031369 translation initiation factor binding
GO:0042795 snRNA transcription by RNA polymerase II
GO:0045948 positive regulation of translational initiation
GO:0048239 negative regulation of DNA recombination at telomere
GO:0050434 positive regulation of viral transcription
GO:0060213 positive regulation of nuclear-transcribed mRNA poly(A) tail shortening
GO:0060964 regulation of gene silencing by miRNA

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR003029 S1 domainDomainDomain
IPR005576 RNA polymerase Rpb7-like , N-terminalDomainDomain
IPR012340 Nucleic acid-binding, OB-foldFamilyHomologous superfamily
IPR022967 RNA-binding domain, S1DomainDomain
IPR036898 RNA polymerase Rpb7-like, N-terminal domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
RPB7_HUMANMCAF1_MOUSEBioGRID10777215 details