Entity Details

Primary name RAN_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP62826
EntryNameRAN_HUMAN
FullNameGTP-binding nuclear protein Ran
TaxID9606
Evidenceevidence at protein level
Length216
SequenceStatuscomplete
DateCreated2004-08-16
DateModified2021-06-02

Ontological Relatives

GenesRAN

GO terms

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GOName
GO:0000054 ribosomal subunit export from nucleus
GO:0000055 ribosomal large subunit export from nucleus
GO:0000056 ribosomal small subunit export from nucleus
GO:0000070 mitotic sister chromatid segregation
GO:0000278 mitotic cell cycle
GO:0000287 magnesium ion binding
GO:0003682 chromatin binding
GO:0003723 RNA binding
GO:0003924 GTPase activity
GO:0005525 GTP binding
GO:0005634 nucleus
GO:0005635 nuclear envelope
GO:0005643 nuclear pore
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005814 centriole
GO:0005829 cytosol
GO:0006259 DNA metabolic process
GO:0006409 tRNA export from nucleus
GO:0006606 protein import into nucleus
GO:0006611 protein export from nucleus
GO:0007052 mitotic spindle organization
GO:0007084 mitotic nuclear membrane reassembly
GO:0010586 miRNA metabolic process
GO:0016020 membrane
GO:0016032 viral process
GO:0019003 GDP binding
GO:0030496 midbody
GO:0032092 positive regulation of protein binding
GO:0032991 protein-containing complex
GO:0035281 pre-miRNA export from nucleus
GO:0042307 positive regulation of protein import into nucleus
GO:0042470 melanosome
GO:0042565 RNA nuclear export complex
GO:0043657 host cell
GO:0045296 cadherin binding
GO:0045540 regulation of cholesterol biosynthetic process
GO:0046039 GTP metabolic process
GO:0046982 protein heterodimerization activity
GO:0051301 cell division
GO:0055037 recycling endosome
GO:0061015 snRNA import into nucleus
GO:0070062 extracellular exosome
GO:0075733 intracellular transport of virus
GO:1902570 protein localization to nucleolus

Subcellular Location

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Subcellular Location
Cytoplasm
Melanosome
Nucleus
Nucleus envelope

Domains

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DomainNameCategoryType
IPR001806 Small GTPaseFamilyFamily
IPR002041 Ran GTPaseFamilyFamily
IPR005225 Small GTP-binding protein domainDomainDomain
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB04315 Guanosine-5'-DiphosphateDrugbanksmall molecule