Entity Details

Primary name AP2B1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP63010
EntryNameAP2B1_HUMAN
FullNameAP-2 complex subunit beta
TaxID9606
Evidenceevidence at protein level
Length937
SequenceStatuscomplete
DateCreated2004-08-31
DateModified2021-06-02

Ontological Relatives

GenesAP2B1

GO terms

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GOName
GO:0001822 kidney development
GO:0003281 ventricular septum development
GO:0005048 signal sequence binding
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006886 intracellular protein transport
GO:0016020 membrane
GO:0016192 vesicle-mediated transport
GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0030122 AP-2 adaptor complex
GO:0030131 clathrin adaptor complex
GO:0030276 clathrin binding
GO:0030666 endocytic vesicle membrane
GO:0030669 clathrin-coated endocytic vesicle membrane
GO:0032802 low-density lipoprotein particle receptor catabolic process
GO:0034383 low-density lipoprotein particle clearance
GO:0035904 aorta development
GO:0036020 endolysosome membrane
GO:0044877 protein-containing complex binding
GO:0045334 clathrin-coated endocytic vesicle
GO:0045807 positive regulation of endocytosis
GO:0048013 ephrin receptor signaling pathway
GO:0048268 clathrin coat assembly
GO:0048488 synaptic vesicle endocytosis
GO:0050690 regulation of defense response to virus by virus
GO:0060071 Wnt signaling pathway, planar cell polarity pathway
GO:0060976 coronary vasculature development
GO:0061024 membrane organization
GO:0072583 clathrin-dependent endocytosis
GO:0098793 presynapse
GO:0098794 postsynapse
GO:0098884 postsynaptic neurotransmitter receptor internalization
GO:0098978 glutamatergic synapse
GO:1901215 negative regulation of neuron death
GO:1905477 positive regulation of protein localization to membrane

Subcellular Location

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Subcellular Location
Cell membrane
Membrane

Domains

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DomainNameCategoryType
IPR000225 ArmadilloRepeatRepeat
IPR002553 Clathrin/coatomer adaptor, adaptin-like, N-terminalDomainDomain
IPR008152 Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomainDomainDomain
IPR009028 Coatomer/calthrin adaptor appendage, C-terminal subdomainFamilyHomologous superfamily
IPR011989 Armadillo-like helicalFamilyHomologous superfamily
IPR012295 TBP domain superfamilyFamilyHomologous superfamily
IPR013037 Clathrin adaptor, beta-adaptin, appendage, Ig-like subdomainFamilyHomologous superfamily
IPR013041 Clathrin adaptor, appendage, Ig-like subdomain superfamilyFamilyHomologous superfamily
IPR015151 Beta-adaptin appendage, C-terminal subdomainDomainDomain
IPR016024 Armadillo-type foldFamilyHomologous superfamily
IPR016342 AP-1/2/4 complex subunit betaFamilyFamily
IPR026739 AP complex subunit betaFamilyFamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
AP2B1_HUMANNECP1_MOUSEDIP24130457 details
AP2B1_HUMANTGFR1_MOUSEDIP26680585 details