Entity Details

Primary name GNAI1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP63096
EntryNameGNAI1_HUMAN
FullNameGuanine nucleotide-binding protein G(i) subunit alpha-1
TaxID9606
Evidenceevidence at protein level
Length354
SequenceStatuscomplete
DateCreated1987-08-13
DateModified2021-06-02

Ontological Relatives

GenesGNAI1

GO terms

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GOName
GO:0000287 magnesium ion binding
GO:0001664 G protein-coupled receptor binding
GO:0003924 GTPase activity
GO:0005525 GTP binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005765 lysosomal membrane
GO:0005813 centrosome
GO:0005834 heterotrimeric G-protein complex
GO:0005886 plasma membrane
GO:0006457 protein folding
GO:0007049 cell cycle
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway
GO:0007193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway
GO:0019003 GDP binding
GO:0030168 platelet activation
GO:0030496 midbody
GO:0031683 G-protein beta/gamma-subunit complex binding
GO:0031821 G protein-coupled serotonin receptor binding
GO:0032794 GTPase activating protein binding
GO:0043434 response to peptide hormone
GO:0043949 regulation of cAMP-mediated signaling
GO:0045121 membrane raft
GO:0050805 negative regulation of synaptic transmission
GO:0051301 cell division
GO:0060236 regulation of mitotic spindle organization
GO:0070062 extracellular exosome
GO:0099738 cell cortex region
GO:1904322 cellular response to forskolin
GO:1904778 positive regulation of protein localization to cell cortex

Subcellular Location

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Subcellular Location
Cell membrane
Cytoplasm
Membrane
Nucleus

Domains

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DomainNameCategoryType
IPR001019 Guanine nucleotide binding protein (G-protein), alpha subunitFamilyFamily
IPR001408 G-protein alpha subunit, group IFamilyFamily
IPR011025 G protein alpha subunit, helical insertionFamilyHomologous superfamily
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB04315 Guanosine-5'-DiphosphateDrugbanksmall molecule
DB04444 Tetrafluoroaluminate IonDrugbanksmall molecule

Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink