Entity Details

Primary name ACTG_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP63261
EntryNameACTG_HUMAN
FullNameActin, cytoplasmic 2
TaxID9606
Evidenceevidence at protein level
Length375
SequenceStatuscomplete
DateCreated1986-07-21
DateModified2021-06-02

Ontological Relatives

GenesACTG1

GO terms

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GOName
GO:0001525 angiogenesis
GO:0001738 morphogenesis of a polarized epithelium
GO:0001895 retina homeostasis
GO:0005200 structural constituent of cytoskeleton
GO:0005522 profilin binding
GO:0005524 ATP binding
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005829 cytosol
GO:0005856 cytoskeleton
GO:0005884 actin filament
GO:0005886 plasma membrane
GO:0005911 cell-cell junction
GO:0005925 focal adhesion
GO:0010628 positive regulation of gene expression
GO:0016020 membrane
GO:0030335 positive regulation of cell migration
GO:0031625 ubiquitin protein ligase binding
GO:0034329 cell junction assembly
GO:0035633 maintenance of blood-brain barrier
GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis
GO:0042802 identical protein binding
GO:0043296 apical junction complex
GO:0048013 ephrin receptor signaling pathway
GO:0051492 regulation of stress fiber assembly
GO:0051893 regulation of focal adhesion assembly
GO:0061024 membrane organization
GO:0070062 extracellular exosome
GO:0070527 platelet aggregation
GO:0072562 blood microparticle
GO:0090303 positive regulation of wound healing
GO:0097433 dense body
GO:0098973 structural constituent of postsynaptic actin cytoskeleton
GO:0120192 tight junction assembly
GO:0150111 regulation of transepithelial transport
GO:1902396 protein localization to bicellular tight junction

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR004000 Actin familyFamilyFamily
IPR004001 Actin, conserved siteSiteConserved site
IPR020902 Actin/actin-like conserved siteSiteConserved site
IPR043129 ATPase, nucleotide binding domainFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB09130 CopperDrugbanksmall molecule
DB11638 ArtenimolDrugbanksmall molecule

Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
ACTG_HUMANPPARG_MOUSEBioGRID27197753 details