Entity Details

Primary name ACTS_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP68133
EntryNameACTS_HUMAN
FullNameActin, alpha skeletal muscle
TaxID9606
Evidenceevidence at protein level
Length377
SequenceStatuscomplete
DateCreated1986-07-21
DateModified2021-06-02

Ontological Relatives

GenesACTA1

GO terms

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GOName
GO:0001725 stress fiber
GO:0005200 structural constituent of cytoskeleton
GO:0005524 ATP binding
GO:0005615 extracellular space
GO:0005829 cytosol
GO:0005865 striated muscle thin filament
GO:0005869 dynactin complex
GO:0005884 actin filament
GO:0006936 muscle contraction
GO:0009612 response to mechanical stimulus
GO:0009991 response to extracellular stimulus
GO:0010226 response to lithium ion
GO:0010628 positive regulation of gene expression
GO:0015629 actin cytoskeleton
GO:0017022 myosin binding
GO:0030017 sarcomere
GO:0030027 lamellipodium
GO:0030049 muscle filament sliding
GO:0030175 filopodium
GO:0030240 skeletal muscle thin filament assembly
GO:0043503 skeletal muscle fiber adaptation
GO:0043531 ADP binding
GO:0044297 cell body
GO:0048545 response to steroid hormone
GO:0048741 skeletal muscle fiber development
GO:0070062 extracellular exosome
GO:0071417 cellular response to organonitrogen compound
GO:0072562 blood microparticle
GO:0090131 mesenchyme migration

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR004000 Actin familyFamilyFamily
IPR004001 Actin, conserved siteSiteConserved site
IPR020902 Actin/actin-like conserved siteSiteConserved site
IPR043129 ATPase, nucleotide binding domainFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB02621 Latrunculin ADrugbanksmall molecule
DB02772 SucroseDrugbanksmall molecule
DB03021 Ulapualide ADrugbanksmall molecule
DB03616 Kabiramide CDrugbanksmall molecule
DB03850 Jaspisamide ADrugbanksmall molecule
DB03903 TmrDrugbanksmall molecule
DB04151 1-MethylhistidineDrugbanksmall molecule
DB04395 Phosphoaminophosphonic Acid-Adenylate EsterDrugbanksmall molecule
DB04629 Aplyronine ADrugbanksmall molecule
DB04774 Reidispongiolide ADrugbanksmall molecule
DB04775 Reidispongiolide CDrugbanksmall molecule
DB04783 Sphinxolide BDrugbanksmall molecule
DB08080 Latrunculin BDrugbanksmall molecule

Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
ACTS_HUMANKCMA1_MOUSEMINT17065230 details