Entity Details

Primary name TBB4B_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP68371
EntryNameTBB4B_HUMAN
FullNameTubulin beta-4B chain
TaxID9606
Evidenceevidence at protein level
Length445
SequenceStatuscomplete
DateCreated1987-08-13
DateModified2021-06-02

Ontological Relatives

GenesTUBB4B

GO terms

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GOName
GO:0000086 G2/M transition of mitotic cell cycle
GO:0000226 microtubule cytoskeleton organization
GO:0000278 mitotic cell cycle
GO:0003725 double-stranded RNA binding
GO:0003924 GTPase activity
GO:0005200 structural constituent of cytoskeleton
GO:0005525 GTP binding
GO:0005576 extracellular region
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005856 cytoskeleton
GO:0005874 microtubule
GO:0010389 regulation of G2/M transition of mitotic cell cycle
GO:0035578 azurophil granule lumen
GO:0042267 natural killer cell mediated cytotoxicity
GO:0042288 MHC class I protein binding
GO:0043312 neutrophil degranulation
GO:0051082 unfolded protein binding
GO:0070062 extracellular exosome
GO:0097711 ciliary basal body-plasma membrane docking
GO:1903561 extracellular vesicle

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR000217 TubulinFamilyFamily
IPR002453 Beta tubulinFamilyFamily
IPR003008 Tubulin/FtsZ, GTPase domainDomainDomain
IPR008280 Tubulin/FtsZ, C-terminalFamilyHomologous superfamily
IPR013838 Beta tubulin, autoregulation binding siteSiteBinding site
IPR017975 Tubulin, conserved siteSiteConserved site
IPR018316 Tubulin/FtsZ, 2-layer sandwich domainDomainDomain
IPR023123 Tubulin, C-terminalFamilyHomologous superfamily
IPR036525 Tubulin/FtsZ, GTPase domain superfamilyFamilyHomologous superfamily
IPR037103 Tubulin/FtsZ-like, C-terminal domainFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00518 AlbendazoleDrugbanksmall molecule
DB00643 MebendazoleDrugbanksmall molecule
DB01873 Epothilone DDrugbanksmall molecule
DB03010 PatupiloneDrugbanksmall molecule
DB04910 OxibendazoleDrugbanksmall molecule
DB05147 CYT997Drugbanksmall molecule
DB12695 Phenethyl IsothiocyanateDrugbanksmall molecule

Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
TBB4B_HUMANYAP1_MOUSEBioGRID30865227 details