Entity Details

Primary name GELS_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP13020
EntryNameGELS_MOUSE
FullNameGelsolin
TaxID10090
Evidenceevidence at protein level
Length780
SequenceStatuscomplete
DateCreated1990-01-01
DateModified2021-06-02

Ontological Relatives

GenesGsn

GO terms

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GOName
GO:0001726 ruffle
GO:0002102 podosome
GO:0003779 actin binding
GO:0005509 calcium ion binding
GO:0005546 phosphatidylinositol-4,5-bisphosphate binding
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006911 phagocytosis, engulfment
GO:0006915 apoptotic process
GO:0007417 central nervous system development
GO:0007568 aging
GO:0008154 actin polymerization or depolymerization
GO:0010628 positive regulation of gene expression
GO:0014003 oligodendrocyte development
GO:0014891 striated muscle atrophy
GO:0015629 actin cytoskeleton
GO:0016192 vesicle-mediated transport
GO:0016528 sarcoplasm
GO:0030027 lamellipodium
GO:0030031 cell projection assembly
GO:0030036 actin cytoskeleton organization
GO:0030041 actin filament polymerization
GO:0030042 actin filament depolymerization
GO:0030155 regulation of cell adhesion
GO:0030478 actin cap
GO:0030864 cortical actin cytoskeleton
GO:0031648 protein destabilization
GO:0032991 protein-containing complex
GO:0035994 response to muscle stretch
GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding
GO:0042060 wound healing
GO:0042246 tissue regeneration
GO:0042989 sequestering of actin monomers
GO:0043209 myelin sheath
GO:0045010 actin nucleation
GO:0045159 myosin II binding
GO:0045335 phagocytic vesicle
GO:0045471 response to ethanol
GO:0046597 negative regulation of viral entry into host cell
GO:0048015 phosphatidylinositol-mediated signaling
GO:0048471 perinuclear region of cytoplasm
GO:0051014 actin filament severing
GO:0051015 actin filament binding
GO:0051016 barbed-end actin filament capping
GO:0051127 positive regulation of actin nucleation
GO:0051593 response to folic acid
GO:0051693 actin filament capping
GO:0055119 relaxation of cardiac muscle
GO:0060271 cilium assembly
GO:0071276 cellular response to cadmium ion
GO:0071346 cellular response to interferon-gamma
GO:0071801 regulation of podosome assembly
GO:0086003 cardiac muscle cell contraction
GO:0090527 actin filament reorganization
GO:0097017 renal protein absorption
GO:0097284 hepatocyte apoptotic process
GO:1902174 positive regulation of keratinocyte apoptotic process
GO:1903903 regulation of establishment of T cell polarity
GO:1903906 regulation of plasma membrane raft polarization
GO:1903909 regulation of receptor clustering
GO:1903923 positive regulation of protein processing in phagocytic vesicle
GO:1990000 amyloid fibril formation
GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

Subcellular Location

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Subcellular Location
Cytoplasm
Secreted

Domains

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DomainNameCategoryType
IPR007122 Villin/GelsolinFamilyFamily
IPR007123 Gelsolin-like domainDomainDomain
IPR029006 ADF-H/Gelsolin-like domain superfamilyFamilyHomologous superfamily
IPR030004 GelsolinFamilyFamily

Diseases

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