Entity Details

Primary name PRAME_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP78395
EntryNamePRAME_HUMAN
FullNameMelanoma antigen preferentially expressed in tumors
TaxID9606
Evidenceevidence at protein level
Length509
SequenceStatuscomplete
DateCreated2000-05-30
DateModified2021-06-02

Ontological Relatives

GenesPRAME

GO terms

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GOName
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0006915 apoptotic process
GO:0008284 positive regulation of cell population proliferation
GO:0030154 cell differentiation
GO:0040008 regulation of growth
GO:0042974 retinoic acid receptor binding
GO:0043066 negative regulation of apoptotic process
GO:0045596 negative regulation of cell differentiation
GO:0045892 negative regulation of transcription, DNA-templated
GO:0048387 negative regulation of retinoic acid receptor signaling pathway

Subcellular Location

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Subcellular Location
Cell membrane
Nucleus

Domains

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DomainNameCategoryType
IPR026271 PRAME familyFamilyFamily
IPR032675 Leucine-rich repeat domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
PRAME_HUMANHACD3_MOUSEIntAct25036637 details