Entity Details

Primary name ARF1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP84077
EntryNameARF1_HUMAN
FullNameADP-ribosylation factor 1
TaxID9606
Evidenceevidence at protein level
Length181
SequenceStatuscomplete
DateCreated2004-08-16
DateModified2021-06-02

Ontological Relatives

GenesARF1

GO terms

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GOName
GO:0000139 Golgi membrane
GO:0000287 magnesium ion binding
GO:0002090 regulation of receptor internalization
GO:0003723 RNA binding
GO:0005525 GTP binding
GO:0005770 late endosome
GO:0005778 peroxisomal membrane
GO:0005802 trans-Golgi network
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005925 focal adhesion
GO:0006661 phosphatidylinositol biosynthetic process
GO:0006878 cellular copper ion homeostasis
GO:0006886 intracellular protein transport
GO:0006892 post-Golgi vesicle-mediated transport
GO:0007015 actin filament organization
GO:0014069 postsynaptic density
GO:0016192 vesicle-mediated transport
GO:0019003 GDP binding
GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0019904 protein domain specific binding
GO:0030017 sarcomere
GO:0030137 COPI-coated vesicle
GO:0031252 cell leading edge
GO:0032991 protein-containing complex
GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation
GO:0034379 very-low-density lipoprotein particle assembly
GO:0035722 interleukin-12-mediated signaling pathway
GO:0043005 neuron projection
GO:0045807 positive regulation of endocytosis
GO:0045956 positive regulation of calcium ion-dependent exocytosis
GO:0048471 perinuclear region of cytoplasm
GO:0050690 regulation of defense response to virus by virus
GO:0050714 positive regulation of protein secretion
GO:0055108 Golgi to transport vesicle transport
GO:0060292 long-term synaptic depression
GO:0060999 positive regulation of dendritic spine development
GO:0070062 extracellular exosome
GO:0070142 synaptic vesicle budding
GO:0097061 dendritic spine organization
GO:0097212 lysosomal membrane organization
GO:0098586 cellular response to virus
GO:0098974 postsynaptic actin cytoskeleton organization
GO:0098978 glutamatergic synapse
GO:1902307 positive regulation of sodium ion transmembrane transport
GO:1902824 positive regulation of late endosome to lysosome transport
GO:1902953 positive regulation of ER to Golgi vesicle-mediated transport
GO:1903725 regulation of phospholipid metabolic process
GO:1990386 mitotic cleavage furrow ingression
GO:1990583 phospholipase D activator activity

Subcellular Location

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Subcellular Location
Cell junction
Cytoplasm
Golgi apparatus
Membrane

Domains

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DomainNameCategoryType
IPR005225 Small GTP-binding protein domainDomainDomain
IPR006689 Small GTPase superfamily, ARF/SAR typeFamilyFamily
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB02774 1,3-PropanediolDrugbanksmall molecule
DB04121 Guanosine-3'-monophosphate-5'-diphosphateDrugbanksmall molecule
DB04137 Guanosine-5'-TriphosphateDrugbanksmall molecule
DB04315 Guanosine-5'-DiphosphateDrugbanksmall molecule
DB07348 Brefeldin ADrugbanksmall molecule
DB08231 Myristic acidDrugbanksmall molecule
DB09462 GlycerinDrugbanksmall molecule

Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
ARF1_HUMANASAP1_MOUSEIntAct9819391 details