Entity Details

Primary name UMPS_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP13439
EntryNameUMPS_MOUSE
FullNameUridine 5'-monophosphate synthase
TaxID10090
Evidenceevidence at protein level
Length481
SequenceStatuscomplete
DateCreated1990-01-01
DateModified2021-06-02

Ontological Relatives

GenesUmps

GO terms

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GOName
GO:0004588 orotate phosphoribosyltransferase activity
GO:0004590 orotidine-5'-phosphate decarboxylase activity
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process
GO:0006222 UMP biosynthetic process
GO:0007565 female pregnancy
GO:0007595 lactation
GO:0009116 nucleoside metabolic process
GO:0019856 pyrimidine nucleobase biosynthetic process
GO:0035690 cellular response to drug
GO:0042802 identical protein binding
GO:0044205 'de novo' UMP biosynthetic process

Subcellular Location

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Domains

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DomainNameCategoryType
IPR000836 Phosphoribosyltransferase domainDomainDomain
IPR001754 Orotidine 5'-phosphate decarboxylase domainDomainDomain
IPR004467 Orotate phosphoribosyl transferase domainDomainDomain
IPR011060 Ribulose-phosphate binding barrelFamilyHomologous superfamily
IPR013785 Aldolase-type TIM barrelFamilyHomologous superfamily
IPR014732 Orotidine 5'-phosphate decarboxylaseFamilyFamily
IPR018089 Orotidine 5'-phosphate decarboxylase, active siteSiteActive site
IPR023031 Orotate phosphoribosyltransferaseFamilyFamily
IPR029057 Phosphoribosyltransferase-likeFamilyHomologous superfamily

Diseases

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Interactions

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