Entity Details

Primary name ICAM1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP13597
EntryNameICAM1_MOUSE
FullNameIntercellular adhesion molecule 1
TaxID10090
Evidenceevidence at protein level
Length537
SequenceStatuscomplete
DateCreated1990-01-01
DateModified2021-06-02

Ontological Relatives

GenesIcam1

GO terms

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GOName
GO:0001772 immunological synapse
GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell
GO:0002438 acute inflammatory response to antigenic stimulus
GO:0002457 T cell antigen processing and presentation
GO:0002693 positive regulation of cellular extravasation
GO:0005178 integrin binding
GO:0005615 extracellular space
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0007155 cell adhesion
GO:0007159 leukocyte cell-cell adhesion
GO:0007605 sensory perception of sound
GO:0008360 regulation of cell shape
GO:0009897 external side of plasma membrane
GO:0009986 cell surface
GO:0022614 membrane to membrane docking
GO:0030838 positive regulation of actin filament polymerization
GO:0033627 cell adhesion mediated by integrin
GO:0043547 positive regulation of GTPase activity
GO:0044406 adhesion of symbiont to host
GO:0044877 protein-containing complex binding
GO:0045429 positive regulation of nitric oxide biosynthetic process
GO:0045907 positive regulation of vasoconstriction
GO:0046813 receptor-mediated virion attachment to host cell
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation
GO:0051092 positive regulation of NF-kappaB transcription factor activity
GO:0051926 negative regulation of calcium ion transport
GO:0061028 establishment of endothelial barrier
GO:0070062 extracellular exosome
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0071333 cellular response to glucose stimulus
GO:0072683 T cell extravasation
GO:0090557 establishment of endothelial intestinal barrier
GO:0097368 establishment of Sertoli cell barrier
GO:0098609 cell-cell adhesion
GO:1900027 regulation of ruffle assembly
GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:1904646 cellular response to amyloid-beta
GO:1904996 positive regulation of leukocyte adhesion to vascular endothelial cell
GO:1990830 cellular response to leukemia inhibitory factor
GO:2000352 negative regulation of endothelial cell apoptotic process

Subcellular Location

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Subcellular Location
Membrane

Domains

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DomainNameCategoryType
IPR003599 Immunoglobulin subtypeDomainDomain
IPR003987 Intercellular adhesion molecule/vascular cell adhesion molecule, N-terminalDomainDomain
IPR003988 Intercellular adhesion moleculeDomainDomain
IPR007110 Immunoglobulin-like domainDomainDomain
IPR013768 Intercellular adhesion molecule, N-terminalDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR036179 Immunoglobulin-like domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
ICAM1_MOUSERADI_MOUSEDIP16615918 details