Entity Details

Primary name SPTB2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ01082
EntryNameSPTB2_HUMAN
FullNameSpectrin beta chain, non-erythrocytic 1
TaxID9606
Evidenceevidence at protein level
Length2364
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesSPTBN1

GO terms

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GOName
GO:0000165 MAPK cascade
GO:0000281 mitotic cytokinesis
GO:0003723 RNA binding
GO:0003779 actin binding
GO:0005200 structural constituent of cytoskeleton
GO:0005516 calmodulin binding
GO:0005543 phospholipid binding
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport
GO:0007009 plasma membrane organization
GO:0007411 axon guidance
GO:0008091 spectrin
GO:0014731 spectrin-associated cytoskeleton
GO:0030506 ankyrin binding
GO:0030673 axolemma
GO:0031430 M band
GO:0032743 positive regulation of interleukin-2 production
GO:0043001 Golgi to plasma membrane protein transport
GO:0045296 cadherin binding
GO:0051020 GTPase binding
GO:0051693 actin filament capping
GO:0070062 extracellular exosome
GO:0071709 membrane assembly
GO:0072659 protein localization to plasma membrane
GO:1903076 regulation of protein localization to plasma membrane
GO:1903078 positive regulation of protein localization to plasma membrane

Subcellular Location

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Subcellular Location
Cell membrane
Cytoplasm

Domains

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DomainNameCategoryType
IPR001589 Actinin-type actin-binding domain, conserved siteSiteConserved site
IPR001605 Pleckstrin homology domain, spectrin-typeDomainDomain
IPR001715 Calponin homology domainDomainDomain
IPR001849 Pleckstrin homology domainDomainDomain
IPR002017 Spectrin repeatRepeatRepeat
IPR011993 PH-like domain superfamilyFamilyHomologous superfamily
IPR016343 Spectrin, beta subunitFamilyFamily
IPR018159 Spectrin/alpha-actininRepeatRepeat
IPR036872 CH domain superfamilyFamilyHomologous superfamily
IPR041681 Pleckstrin homology domain 9DomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB01373 CalciumDrugbanksmall molecule
DB03401 1D-myo-inositol 1,4,5-trisphosphateDrugbanksmall molecule

Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink