Entity Details

Primary name FLI1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ01543
EntryNameFLI1_HUMAN
FullNameFriend leukemia integration 1 transcription factor
TaxID9606
Evidenceevidence at protein level
Length452
SequenceStatuscomplete
DateCreated1993-07-01
DateModified2021-06-02

Ontological Relatives

GenesFLI1

GO terms

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GOName
GO:0000785 chromatin
GO:0000976 transcription cis-regulatory region binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005829 cytosol
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007599 hemostasis
GO:0008015 blood circulation
GO:0009887 animal organ morphogenesis
GO:0016604 nuclear body
GO:0030154 cell differentiation
GO:0035855 megakaryocyte development
GO:0045893 positive regulation of transcription, DNA-templated
GO:1990837 sequence-specific double-stranded DNA binding

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR000418 Ets domainDomainDomain
IPR003118 Pointed domainDomainDomain
IPR013761 Sterile alpha motif/pointed domain superfamilyFamilyHomologous superfamily
IPR035573 Friend leukemia integration 1 transcription factor, pointed domainDomainDomain
IPR035575 Friend leukemia integration 1 transcription factorFamilyFamily
IPR036388 Winged helix-like DNA-binding domain superfamilyFamilyHomologous superfamily
IPR036390 Winged helix DNA-binding domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
FLI1_HUMANGRIP1_MOUSEIntAct16990252 details