Entity Details

Primary name MEF2A_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ02078
EntryNameMEF2A_HUMAN
FullNameMyocyte-specific enhancer factor 2A
TaxID9606
Evidenceevidence at protein level
Length507
SequenceStatuscomplete
DateCreated1995-11-01
DateModified2021-06-02

Ontological Relatives

GenesMEF2A

GO terms

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GOName
GO:0000002 mitochondrial genome maintenance
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000165 MAPK cascade
GO:0000785 chromatin
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0003682 chromatin binding
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005667 transcription regulator complex
GO:0005829 cytosol
GO:0006351 transcription, DNA-templated
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006915 apoptotic process
GO:0007507 heart development
GO:0007517 muscle organ development
GO:0010613 positive regulation of cardiac muscle hypertrophy
GO:0010628 positive regulation of gene expression
GO:0019901 protein kinase binding
GO:0030154 cell differentiation
GO:0035035 histone acetyltransferase binding
GO:0042826 histone deacetylase binding
GO:0043565 sequence-specific DNA binding
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046326 positive regulation of glucose import
GO:0046332 SMAD binding
GO:0046982 protein heterodimerization activity
GO:0048311 mitochondrion distribution
GO:0048813 dendrite morphogenesis
GO:0051149 positive regulation of muscle cell differentiation
GO:0055005 ventricular cardiac myofibril assembly
GO:0061337 cardiac conduction
GO:0070375 ERK5 cascade
GO:0071277 cellular response to calcium ion

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR002100 Transcription factor, MADS-boxDomainDomain
IPR022102 Holliday junction regulator protein family C-terminalDomainDomain
IPR033896 MADS MEF2-likeDomainDomain
IPR036879 Transcription factor, MADS-box superfamilyFamilyHomologous superfamily

Diseases

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