Entity Details

Primary name DYST_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ03001
EntryNameDYST_HUMAN
FullNameDystonin
TaxID9606
Evidenceevidence at protein level
Length7570
SequenceStatuscomplete
DateCreated1996-10-01
DateModified2021-06-02

Ontological Relatives

GenesDST

GO terms

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GOName
GO:0000226 microtubule cytoskeleton organization
GO:0003779 actin binding
GO:0005178 integrin binding
GO:0005198 structural molecule activity
GO:0005509 calcium ion binding
GO:0005604 basement membrane
GO:0005634 nucleus
GO:0005635 nuclear envelope
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005789 endoplasmic reticulum membrane
GO:0005829 cytosol
GO:0005882 intermediate filament
GO:0005925 focal adhesion
GO:0005938 cell cortex
GO:0007010 cytoskeleton organization
GO:0007155 cell adhesion
GO:0007229 integrin-mediated signaling pathway
GO:0008017 microtubule binding
GO:0008022 protein C-terminus binding
GO:0008090 retrograde axonal transport
GO:0009611 response to wounding
GO:0009925 basal plasma membrane
GO:0015629 actin cytoskeleton
GO:0015630 microtubule cytoskeleton
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0030011 maintenance of cell polarity
GO:0030018 Z disc
GO:0030056 hemidesmosome
GO:0030199 collagen fibril organization
GO:0030424 axon
GO:0031122 cytoplasmic microtubule organization
GO:0031252 cell leading edge
GO:0031410 cytoplasmic vesicle
GO:0031581 hemidesmosome assembly
GO:0031673 H zone
GO:0035371 microtubule plus-end
GO:0042060 wound healing
GO:0042803 protein homodimerization activity
GO:0045104 intermediate filament cytoskeleton organization
GO:0045111 intermediate filament cytoskeleton
GO:0048870 cell motility
GO:0051010 microtubule plus-end binding
GO:1904115 axon cytoplasm

Subcellular Location

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Subcellular Location
Cell junction
Cell membrane
Cell projection
Cytoplasm
Endoplasmic reticulum membrane
Membrane
Nucleus
Nucleus envelope

Domains

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DomainNameCategoryType
IPR001101 Plectin repeatRepeatRepeat
IPR001452 SH3 domainDomainDomain
IPR001589 Actinin-type actin-binding domain, conserved siteSiteConserved site
IPR001715 Calponin homology domainDomainDomain
IPR002017 Spectrin repeatRepeatRepeat
IPR002048 EF-hand domainDomainDomain
IPR003108 GAR domainDomainDomain
IPR011992 EF-hand domain pairFamilyHomologous superfamily
IPR018159 Spectrin/alpha-actininRepeatRepeat
IPR018247 EF-Hand 1, calcium-binding siteSiteBinding site
IPR035915 Plakin repeat superfamilyFamilyHomologous superfamily
IPR036534 GAR domain superfamilyFamilyHomologous superfamily
IPR036872 CH domain superfamilyFamilyHomologous superfamily
IPR041573 Desmoplakin, spectrin-like domainDomainDomain
IPR041615 Desmoplakin, SH3 domainDomainDomain
IPR043197 PlakinFamilyFamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
DYST_HUMANMARE1_MOUSEBioGRID, IntAct, MINT22995871 26496610 details